{"id":3865,"date":"2017-06-26T15:50:00","date_gmt":"2017-06-26T19:50:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/tarc\/clinical-trials\/"},"modified":"2018-09-14T10:41:08","modified_gmt":"2018-09-14T14:41:08","slug":"clinical-trials-post","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/tarc\/clinical-trials-post\/","title":{"rendered":"Saira Sheikh, MD, pursues unique, \u201cnext generation\u201d clinical trials focusing on direct molecular pathways to find new ways to treat lupus"},"content":{"rendered":"
\n

Innovative approaches to research may lead to changes in the way this disease is treated in the future.<\/p>\n

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\"image2\"
Saira Sheik, MD<\/figcaption><\/figure>\n<\/div>\n
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Historically, treatment options for lupus have been limited to medications borrowed from other disease states such as arthritis, cancer, and organ transplant \u2013 to name a few.<\/p>\n

To pursue a more direct treatment approach, clinical trials being conducted at the UNC Thurston Arthritis Research Center (TARC) are exploring novel and innovative therapies that specifically target molecular pathways involved in the pathogenesis of lupus. In addition, they provide hope and options for patients who are refractory to currently available therapies. The goal is to develop highly targeted approaches tailored to treat the specific manifestations of this very heterogeneous disease with fewer side effects.<\/p>\n

\u201cWe are exploring very direct, specific and innovative approaches that we hope will change the way lupus is treated, and ultimately transform the lives of our patients,\u201d said Saira Sheikh, MD,<\/a> Director of the TARC Clinical Trials Program<\/a>.<\/p>\n

In addition to lupus, examples of TARC\u2019s core areas of clinical and research expertise include: environmental, stinging insect, drug and food allergies; asthma; urticaria and angioedema; immunodeficiency; osteoarthritis; rheumatoid and psoriatic arthritis; gout and other crystal arthropathies; vasculitis; spondyloarthropathies; scleroderma; Sjogren\u2019s syndrome; and many others.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

<\/p>\n

Innovative approaches to research may lead to changes in the way this disease is treated in the future.<\/p>\n","protected":false},"author":1369,"featured_media":3866,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[2],"tags":[4],"class_list":["post-3865","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-research-news","odd"],"acf":[],"yoast_head":"\nSaira Sheikh, MD, pursues unique, \u201cnext generation\u201d clinical trials focusing on direct molecular pathways to find new ways to treat lupus | Thurston Arthritis Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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