{"id":12088,"date":"2021-07-19T18:42:39","date_gmt":"2021-07-19T22:42:39","guid":{"rendered":"https:\/\/www.med.unc.edu\/tarc\/?post_type=tribe_events&p=12088"},"modified":"2022-07-28T13:34:10","modified_gmt":"2022-07-28T17:34:10","slug":"tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced","status":"publish","type":"tribe_events","link":"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/","title":{"rendered":"TARC Research Seminar: Dr. Doug Phanstiel; “Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis”"},"content":{"rendered":"

“Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis”<\/p>\n

Genome-wide association studies (GWAS) have identified over 100 osteoarthritis (OA)-associated loci; however, translating these broad loci into actionable therapeutic targets requires identifying the causal variants, the gene(s) they affect, and their mechanistic impact on OA risk. We apply genomic, bioinformatics, and genome editing approaches to identify novel OA risk genes for further study and therapeutic development.<\/p>\n

Dr. Doug Phanstiel<\/p>\n

Assistant Professor of Cell Biology & Physiology<\/p>\n

UNC Chapel Hill<\/p>\n

Attend Live in TARC Dickson Conference Room, or via Zoom<\/strong><\/p>\n\n\n\n
Virtual (Zoom)\u00a0URL: https:\/\/zoom.us\/j\/92101985767?pwd=d3hHbWhHMFlQSm05RmdCVVVmMkVIUT09<\/a><\/p>\n

Meeting ID: 921 0198 5767<\/p>\n

Passcode: 005755<\/p>\n

Phone (New York): 929-205-6099<\/p>\n

Phone (Toll-free): 888-475-4499<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

“Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis” Genome-wide association studies (GWAS) have identified over 100 osteoarthritis (OA)-associated loci; however, translating these broad loci into actionable therapeutic targets requires identifying the causal variants, the gene(s) they affect, and their mechanistic impact on OA risk. We apply genomic, bioinformatics, and genome editing approaches to identify … Read more<\/a><\/p>\n","protected":false},"author":58060,"featured_media":0,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_tribe_events_status":"","_tribe_events_status_reason":"","_tribe_events_is_hybrid":"","_tribe_events_is_virtual":"","_tribe_events_virtual_video_source":"","_tribe_events_virtual_embed_video":"","_tribe_events_virtual_linked_button_text":"","_tribe_events_virtual_linked_button":"","_tribe_events_virtual_show_embed_at":"","_tribe_events_virtual_show_embed_to":[],"_tribe_events_virtual_show_on_event":"","_tribe_events_virtual_show_on_views":"","_tribe_events_virtual_url":"","footnotes":"","_links_to":"","_links_to_target":""},"tags":[],"tribe_events_cat":[22],"class_list":["post-12088","tribe_events","type-tribe_events","status-publish","hentry","tribe_events_cat-tarc-research-seminar","cat_tarc-research-seminar","odd"],"acf":[],"yoast_head":"\nTARC Research Seminar: Dr. Doug Phanstiel; "Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis" | Thurston Arthritis Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"TARC Research Seminar: Dr. Doug Phanstiel; "Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis" | Thurston Arthritis Research Center\" \/>\n<meta property=\"og:description\" content=\"“Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis” Genome-wide association studies (GWAS) have identified over 100 osteoarthritis (OA)-associated loci; however, translating these broad loci into actionable therapeutic targets requires identifying the causal variants, the gene(s) they affect, and their mechanistic impact on OA risk. We apply genomic, bioinformatics, and genome editing approaches to identify … Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/\" \/>\n<meta property=\"og:site_name\" content=\"Thurston Arthritis Research Center\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/unctarc\" \/>\n<meta property=\"article:modified_time\" content=\"2022-07-28T17:34:10+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@UNCTARC\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/\",\"url\":\"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/\",\"name\":\"TARC Research Seminar: Dr. Doug Phanstiel; \\\"Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis\\\" | Thurston Arthritis Research Center\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/tarc\/#website\"},\"datePublished\":\"2021-07-19T22:42:39+00:00\",\"dateModified\":\"2022-07-28T17:34:10+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/tarc\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Events\",\"item\":\"https:\/\/www.med.unc.edu\/tarc\/events\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"TARC Research Seminar: Dr. Doug Phanstiel; “Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis”\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/tarc\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/tarc\/\",\"name\":\"Thurston Arthritis Research Center\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/tarc\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"TARC Research Seminar: Dr. Doug Phanstiel; \"Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis\" | Thurston Arthritis Research Center","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/","og_locale":"en_US","og_type":"article","og_title":"TARC Research Seminar: Dr. Doug Phanstiel; \"Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis\" | Thurston Arthritis Research Center","og_description":"“Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis” Genome-wide association studies (GWAS) have identified over 100 osteoarthritis (OA)-associated loci; however, translating these broad loci into actionable therapeutic targets requires identifying the causal variants, the gene(s) they affect, and their mechanistic impact on OA risk. We apply genomic, bioinformatics, and genome editing approaches to identify … Read more","og_url":"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/","og_site_name":"Thurston Arthritis Research Center","article_publisher":"https:\/\/www.facebook.com\/unctarc","article_modified_time":"2022-07-28T17:34:10+00:00","twitter_card":"summary_large_image","twitter_site":"@UNCTARC","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/","url":"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/","name":"TARC Research Seminar: Dr. Doug Phanstiel; \"Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis\" | Thurston Arthritis Research Center","isPartOf":{"@id":"https:\/\/www.med.unc.edu\/tarc\/#website"},"datePublished":"2021-07-19T22:42:39+00:00","dateModified":"2022-07-28T17:34:10+00:00","breadcrumb":{"@id":"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-saira-sheikh-seminar-title-and-description-to-be-announced\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.med.unc.edu\/tarc\/"},{"@type":"ListItem","position":2,"name":"Events","item":"https:\/\/www.med.unc.edu\/tarc\/events\/"},{"@type":"ListItem","position":3,"name":"TARC Research Seminar: Dr. Doug Phanstiel; “Genomic Approaches to Understanding the Genetic Risk of Osteoarthritis”"}]},{"@type":"WebSite","@id":"https:\/\/www.med.unc.edu\/tarc\/#website","url":"https:\/\/www.med.unc.edu\/tarc\/","name":"Thurston Arthritis Research Center","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.med.unc.edu\/tarc\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/tribe_events\/12088","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/tribe_events"}],"about":[{"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/types\/tribe_events"}],"author":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/users\/58060"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/tribe_events\/12088\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/media?parent=12088"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/tags?post=12088"},{"taxonomy":"tribe_events_cat","embeddable":true,"href":"https:\/\/www.med.unc.edu\/tarc\/wp-json\/wp\/v2\/tribe_events_cat?post=12088"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}