{"id":13937,"date":"2022-08-12T16:00:36","date_gmt":"2022-08-12T20:00:36","guid":{"rendered":"https:\/\/www.med.unc.edu\/tarc\/?post_type=tribe_events&#038;p=13937"},"modified":"2022-12-12T14:09:29","modified_gmt":"2022-12-12T19:09:29","slug":"tarc-research-seminar-dr-brian-diekman-title-of-presentation-to-be-announced-soon","status":"publish","type":"tribe_events","link":"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-brian-diekman-title-of-presentation-to-be-announced-soon\/","title":{"rendered":"TARC Research Seminar: Dr. Brian Diekman; &#8220;DNA Damage and Cellular Senescence in Osteoarthritis Pathophysiology.\u201d"},"content":{"rendered":"<p>&#8220;<em>DNA damage and cellular senescence in osteoarthritis pathophysiology.<\/em>\u201d<\/p>\n<p>Brief Description: Aging is the largest risk factor for osteoarthritis, but the mechanisms responsible for this relationship are unclear. Damaged cells can convert to a phenotypic state known as cellular senescence, and senescent cells are associated with compromised tissue function. This talk will focus on our efforts to understand the accumulation of DNA damage in chondrocytes during aging, and to assess whether the activation of more efficient DNA damage repair has promise as a strategy to limit cellular senescence and osteoarthritis.<\/p>\n<p>Dr. Brian Diekman<br \/>\nAssistant Professor of Biomedical Engineering<br \/>\nUNC-CH &amp; NC State Joint Department of BME<\/p>\n<p><strong>Attend Live in TARC Dickson Conference Room, or via Zoom:\u00a0<\/strong><a href=\"https:\/\/zoom.us\/j\/97841158212?pwd=MTRpRXVUbHJNY1AzTmRuS1lLWjM1QT09\">https:\/\/zoom.us\/j\/97841158212?pwd=MTRpRXVUbHJNY1AzTmRuS1lLWjM1QT09<\/a><\/p>\n<p>Meeting ID: 978 4115 8212<br \/>\nPasscode: 922015<br \/>\nOne tap mobile:<br \/>\n+13017158592,,97841158212#,,,,*922015# US (Washington DC)<br \/>\n+13052241968,,97841158212#,,,,*922015# US<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;DNA damage and cellular senescence in osteoarthritis pathophysiology.\u201d Brief Description: Aging is the largest risk factor for osteoarthritis, but the mechanisms responsible for this relationship are unclear. Damaged cells can convert to a phenotypic state known as cellular senescence, and senescent cells are associated with compromised tissue function. This talk will focus on our efforts &hellip; <a href=\"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-brian-diekman-title-of-presentation-to-be-announced-soon\/\" aria-label=\"Read more about TARC Research Seminar: Dr. Brian Diekman; &#8220;DNA Damage and Cellular Senescence in Osteoarthritis Pathophysiology.\u201d\">Read more<\/a><\/p>\n","protected":false},"author":58060,"featured_media":0,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_tribe_events_status":"","_tribe_events_status_reason":"","_tribe_events_is_hybrid":"","_tribe_events_is_virtual":"","_tribe_events_virtual_video_source":"","_tribe_events_virtual_embed_video":"","_tribe_events_virtual_linked_button_text":"","_tribe_events_virtual_linked_button":"","_tribe_events_virtual_show_embed_at":"","_tribe_events_virtual_show_embed_to":[],"_tribe_events_virtual_show_on_event":"","_tribe_events_virtual_show_on_views":"","_tribe_events_virtual_url":"","footnotes":"","_links_to":"","_links_to_target":""},"tags":[],"tribe_events_cat":[22],"class_list":["post-13937","tribe_events","type-tribe_events","status-publish","hentry","tribe_events_cat-tarc-research-seminar","cat_tarc-research-seminar","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>TARC Research Seminar: Dr. Brian Diekman; &quot;DNA Damage and Cellular Senescence in Osteoarthritis Pathophysiology.\u201d | Thurston Arthritis Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-brian-diekman-title-of-presentation-to-be-announced-soon\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"TARC Research Seminar: Dr. Brian Diekman; &quot;DNA Damage and Cellular Senescence in Osteoarthritis Pathophysiology.\u201d | Thurston Arthritis Research Center\" \/>\n<meta property=\"og:description\" content=\"&#8220;DNA damage and cellular senescence in osteoarthritis pathophysiology.\u201d Brief Description: Aging is the largest risk factor for osteoarthritis, but the mechanisms responsible for this relationship are unclear. 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