{"id":14834,"date":"2023-02-08T10:46:46","date_gmt":"2023-02-08T15:46:46","guid":{"rendered":"https:\/\/www.med.unc.edu\/tarc\/?post_type=tribe_events&#038;p=14834"},"modified":"2023-02-16T16:41:31","modified_gmt":"2023-02-16T21:41:31","slug":"tarc-research-seminar-dr-ming-feng-hsueh-novel-mechanisms-of-microrna-mediated-anabolic-effects-in-osteoarthritis","status":"publish","type":"tribe_events","link":"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-ming-feng-hsueh-novel-mechanisms-of-microrna-mediated-anabolic-effects-in-osteoarthritis\/","title":{"rendered":"TARC Research Seminar: Dr. Ming-Feng Hsueh; &#8220;Novel mechanisms of microRNA-mediated anabolic effects in osteoarthritis&#8221;"},"content":{"rendered":"<p>&#8220;Novel mechanisms of microRNA-mediated anabolic effects in osteoarthritis&#8221;<\/p>\n<p>Brief Description: Through the novel use of in vivo protein deamidation molecular clocks, we unmasked a position-dependent gradient of protein anabolism in human lower limb cartilages. This gradient is strikingly associated with the expression of evolutionarily-conserved limb-regenerative miRNAs. This association shows a potential link to a capacity for regeneration that might be exploited to enhance joint repair.<\/p>\n<p>Dr. Ming-Feng Hsueh, Assistant Professor<br \/>\nDepartment of or of Orthopedic surgery<br \/>\nDuke University<\/p>\n<p>Attend in TARC Dickson Conference room, or remotely.<\/p>\n<p>Join Zoom Meeting\u00a0<a href=\"https:\/\/zoom.us\/j\/97766513682?pwd=ck1OZVNnRFdNNmFHc3gyaUU3TmxDdz09\">https:\/\/zoom.us\/j\/97766513682?pwd=ck1OZVNnRFdNNmFHc3gyaUU3TmxDdz09<\/a><\/p>\n<p>Meeting ID: 977 6651 3682<br \/>\nPasscode: 432508<br \/>\nOne tap mobile<br \/>\n+13017158592,,97766513682#,,,,*432508# US (Washington DC)<br \/>\n+13052241968,,97766513682#,,,,*432508# US<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;Novel mechanisms of microRNA-mediated anabolic effects in osteoarthritis&#8221; Brief Description: Through the novel use of in vivo protein deamidation molecular clocks, we unmasked a position-dependent gradient of protein anabolism in human lower limb cartilages. This gradient is strikingly associated with the expression of evolutionarily-conserved limb-regenerative miRNAs. This association shows a potential link to a capacity &hellip; <a href=\"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-ming-feng-hsueh-novel-mechanisms-of-microrna-mediated-anabolic-effects-in-osteoarthritis\/\" aria-label=\"Read more about TARC Research Seminar: Dr. Ming-Feng Hsueh; &#8220;Novel mechanisms of microRNA-mediated anabolic effects in osteoarthritis&#8221;\">Read more<\/a><\/p>\n","protected":false},"author":58060,"featured_media":0,"template":"","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","_tribe_events_status":"","_tribe_events_status_reason":"","_tribe_events_is_hybrid":"","_tribe_events_is_virtual":"","_tribe_events_virtual_video_source":"","_tribe_events_virtual_embed_video":"","_tribe_events_virtual_linked_button_text":"","_tribe_events_virtual_linked_button":"","_tribe_events_virtual_show_embed_at":"","_tribe_events_virtual_show_embed_to":[],"_tribe_events_virtual_show_on_event":"","_tribe_events_virtual_show_on_views":"","_tribe_events_virtual_url":"","footnotes":"","_links_to":"","_links_to_target":""},"tags":[],"tribe_events_cat":[22],"class_list":["post-14834","tribe_events","type-tribe_events","status-publish","hentry","tribe_events_cat-tarc-research-seminar","cat_tarc-research-seminar","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>TARC Research Seminar: Dr. Ming-Feng Hsueh; &quot;Novel mechanisms of microRNA-mediated anabolic effects in osteoarthritis&quot; | Thurston Arthritis Research Center<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/tarc\/event\/tarc-research-seminar-dr-ming-feng-hsueh-novel-mechanisms-of-microrna-mediated-anabolic-effects-in-osteoarthritis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"TARC Research Seminar: Dr. Ming-Feng Hsueh; &quot;Novel mechanisms of microRNA-mediated anabolic effects in osteoarthritis&quot; | Thurston Arthritis Research Center\" \/>\n<meta property=\"og:description\" content=\"&#8220;Novel mechanisms of microRNA-mediated anabolic effects in osteoarthritis&#8221; Brief Description: Through the novel use of in vivo protein deamidation molecular clocks, we unmasked a position-dependent gradient of protein anabolism in human lower limb cartilages. 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