Office: US EPA Human Studies Facility
Phone: 919-966-1515
Email
Examining underlying mechanisms of lung disease, specifically examining innate immune responses and inflammatory processes in the airways. Also, examining these responses and processes in the context of how inhaled environmental irritants/toxicants produce detrimental effects in the cardiopulmonary system in susceptible populations.
Office: 5109D Neuroscience Research Building
Phone: (919) 843-0842
Email
Cardiovascular biology, cell biology, drug delivery, nanomedicine, translational medicine.
Office: 2253 Mary M. Townes Science Building - NCCU
Phone: (919) 530-6542
Email
Validate novel molecular targets (ex. oncogenic PIM kinases) for potential therapeutic intervention in pancreatic cancer and other cancers as well as test novel kinase inhibitors in combination with chemotherapy to combat drug resistance.
Office: National Institute of Environmental Health Sciences - RTP
Phone: (919) 541-3201
Email
Pharmacokinetic behavior of environmental chemicals, mechanisms of action of toxicants including endocrine disruptors, and linking of real-world exposures to health effects.
Currently not taking student rotations
Office: 100 L Beard Hall
Phone: (919) 962-7030
Email
Hepatobiliary xenobiotic disposition, hepatotoxicity and pharmacokinetics.
Office: Environmental Protection Agency - RTP
Phone: (919) 541-2329
Email
Cell Biology, Genomics, Molecular Biology, Systems Biology, Toxicology.
Office: 1007C Thurston Bowles Building
Phone: 919-966-0501
Email
Immune contributions to disease, extracellular vesicles, neurotoxicology, trauma
Office: National Institute of Environmental Science - RTP
Phone: (984) 287-4215
Email
Pharmacokinetics and mechanisms of chemical-mediated toxicity and carcinogenicity.
Currently not taking student rotations
Office: Environmental Protection Agency - RTP
Phone: (919) 541-5027
Email
Mechanisms of health effects of environmental pollution on cardiopulmonary function, animal models of cardiovascular diseases, targeted and high throughput technology.
Office: National Institute of Environmental Sciences - Durham
Phone: (984) 287-4182
Email
Developmental and Reproductive Toxicology, Environmental Health, Endocrine Disruption, Cancer Susceptibility.
Office: National Institute of Environmental Science - RTP
Phone: (984) 287-3700
Email
Toxicology and Immunology.
Office: National Institute of Environmental Health Science - RTP
Phone: (984) 287-3128
Email
New approach method (NAM) development and qualification for translational toxicology research.
Office: D240 Rall Building
Phone: (984) 287-4081
Email
Mechanisms of induction and regulation of the innate immune response, with a focus on Toll like Receptors (TLRs).
Office: 166A Rosenau Hall
Phone: (919) 843-6864
Email
Toxicogenomic and systems biology approaches to understanding the mechanisms of metal-induced disease and the basis for inter-individual disease susceptibility.
Office: EPA Center for Public Health and Environmental Assessment - RTP
Phone: (919) 541-0015
Email
The interaction between air pollutant exposure and the development of infectious and allergic lung disease.
Office: 157 Rosenau Hall
Phone: (919) 966-7304
Email
Chemistry of protein and DNA adducts.
Currently not taking student rotations
Office: National Institute of Environmental Health Sciences - RTP
Phone: (984) 287-4183
Email
Role of microglia in immune-mediated responses in brain development, repair, aging and disease.
Office: United States Environmental Protection Agency - RTP
Phone: (919) 541-4588
Email
Neurophysiological mechanisms mediating cardiopulmonary dysfunction due to air pollution exposure.
Office: US Environmental Protection Agency
Phone: 919-541-0380
Email
Neurotoxicology, Neurophysiology, Behavior, In Vitro – In Vivo Extrapolation, Developmental Neurotoxicity, Adverse Outcome Pathways, Mixtures
Office: US Environmental Protection Agency
Phone: 919-541-4204
Email: http://mail to:hines.erin@epa.gov
Office: 5077 Genetic Medicine Building
Phone: (919) 445-9047
Email
Developmental Biology, Genetics, Genomics, Molecular Biology.
Office: Kerr Hall, Room 3320
Phone: 919-962-5551
Email
Drug/Xenobiotic Metabolism, Mechanistic Toxicology, Pharmacogenetics
Office: EPA Human Studies Facility
Phone: (919) 966-8657
Email
Mechanisms by which air pollutants enhance susceptibility to and the severity of respiratory virus infections.
Office: 5072 Genetic Medicine Building
Phone: (919) 962-2148
Email
Gene-environment Interactions in Airway Diseases.
Office: U.S. Environmental Protection Agency - RTP
Phone: (919) 541-4963
Email
Cardiovascular disease and susceptibility, air pollutants, cardiopulmonary interactions, molecular mechanisms, genetic and environmental factors.
Office: 5073 Genetic Medicine Building
Phone: (919) 966-0508
Email
Mouse models for human disease, genes that modify disease progression.
Office: 9018B Mary Ellen Jones
Phone: (919) 843-5154
Email
Metabolomics, tissue engineering and systems biology.
Office: United States Environmental Protection Agency - 104 Mason Farm Road
Phone: (919) 966-6257
Email
Mechanisms of ambient air pollutant-induced cardiopulmonary morbidity and mortality.
Currently not taking student rotations
Office: U.S. Environmental Protection Agency - 104 Mason Farm Road, Chapel Hill
Phone: (919) 843-8031
Email
Molecular and mechanistic toxicology, primary and organotypic in vitro models, live cell imaging/fluorescent biosensors, redox dysfunction/oxidative stress, inhalation toxicology, translational research, in vitro to in vivo extrapolation, environmental and public health epigenetics.
Office: 4206B Mary Ellen Jones Building
Phone: 919-445-6822
Email
Environmental determinants of asthma and allergic disease; immunological mechanisms of environmental lung injury.
Office: 3027 Thurston-Bowles
Phone: (919) 966-7682
Email
Neurotoxicology and excitotoxicity of alcohol.
Currently not taking student rotations
Office: 159 Rosenau Hall
Phone: (919) 966-3826
Email
Pharmacogenetics of detoxification pathways in skin and inhalation exposures to toxicants; mathematical and statistical exposure modeling for risk assessment.
Office: 3203 Marsico Hall
Phone: (919) 843-8461
Email
Biochemistry, Biophysics, Cell Biology, Chemical Biology, Drug Discovery.
Office: 546 Human Studies Facility
Phone: (919) 966-0768
Email
Translational and clinical research in environmental lung disease.
Currently not taking student rotations
Office: 347 Rosenau Hall
Phone: (919) 966-4410
Email
Computational toxicology, chemical mixtures, high-throughput exposure science and risk assessment
Office: 32-044 Lineberger Comprehensive Cancer Center
Phone: (919) 966-9839
Email
Mechanisms of chromosome strand break repair.
Office: 1117 Marsico Hall
Phone: (919) 966-8093
Email
Airway epithelial cell biology, pulmonary innate immunity and transplant pathophysiology.
Office: 5004A Mary Ellen Jones Building
Phone: (919) 966-6898
Email
Respiratory immune toxicology, sex differences, clinical and translational research, airway noninvasive sampling methods development.
Office: 9206C Mary Ellen Jones Building
Phone: (919) 966-4934
Email
Biomedical Imaging, Rehabilitation Engineering.
Office: 109 T.W. Alexander Drive
Phone: (919) 541-5177
Email
Currently not taking student rotations
Office: 145 Medical Drive
Phone: (919) 966-0665
Email
Cell and molecular mechanisms of inflammatory responses induced by inhalation of ambient air pollutants.
Office: 3070 Genetic Medicine Building
Phone: (919) 962-0115
Email
Biochemical mechanisms of nucleotide excision repair, DNA damage cell cycle checkpoints, and circadian rhythm.
Office: 4352 Genome Sciences Building
Phone: (919) 962-7010
Email
Crosstalk between immune and nervous systems; macrophages and microglia; inflammation; vertebrate development.
Office: 5070E Genetics Medicine Building
Phone: 973-459-8881
Email
Inhalation toxicology, inhalational exposures, genetic susceptibility, extracellular vesicles, small RNA, lung disease, respiratory physiology, in vivo models
Office: 1309 Kerr Hall
Phone: (919) 962-0095
Email
Establishing quantitative methods for proteins associated with drug disposition, understanding factors influencing the disposition, pharmacokinetics, reactivity and potential toxicity of labile acyl glucuronide metabolites, the role of glucuronidation in intestinal toxicity of drugs and the modulation of drug glucuronidation by botanicals/herbal remedies.
Office: 2302 Michael Hooker Research Center
Phone: (919) 966-5721
Email
Metabolic interactions of essential microelements, especially trace metals, with toxic metals and metalloids that contaminate food and drinking water.
Office:
Phone:
Email
Clinical and translational research on the cardiovascular effects of environmental pollutants; Interventional strategies to mitigate the adverse health effects from air pollution exposure.
Office: National Institute of Environmental Health Sciences - RTP
Phone: (984) 287-3826
Email
The Clinical Pathology Group provides collaborative and consultative clinical pathology support for investigators at NIEHS.
Office: 100K Beard Hall
Phone: (919) 966-2955
Email
Biomolecular informatics; molecular structure-function modeling using statistical and machine learning approaches.
Office: 614A Brinkhous-Bullitt
Phone: (919) 843-9639
Email
Defining DNA Repair Dependencies and Vulnerabilities of Cancer Cells
Office: 104 Mason Farm Road
Phone: (919) 966-5445
Email
Dr. Cavin Ward-Caviness uses high-dimensional ‘omics data and large cohorts to study two major research themes: 1) determination of the molecular mechanisms linking environmental exposures and adverse health and 2) identification of molecular and clinical factors which may increase sensitivity to environmental exposures.
Office: Institute for Drug Safety Sciences - RTP
Phone: (919) 226-3140
Email
Mechanistic toxicology, hepatic toxicology, research translation, biomarkers.
Office: 31-321 Lineberger Comprehensive Cancer Center
Phone: (919) 966-7533
Email
Chromatin remodeling and epigenetic alterations in human cancers.
Office: E448B Rall Building - RTP
Phone: (984) 287-4313
Email
Basic reproductive biology of early mammalian embryogenesis, epigenetics, and how the environment impacts reproduction.
Office: 7008B Mary Ellen Jones Building
Phone: (919) 966-2540
Email
Identifying and studying environmental risks implicated in neurodevelopmental disorders; autism mouse models, Crispr/Cas9 based gene therapies, machine learning algorithms to quantify pain severity, single cell RNA-seq.