Curriculum Member Profiles
Office: 2253 Mary M. Townes Science Building - NCCU
Phone: (919) 530-6542
Validate novel molecular targets (ex. oncogenic PIM kinases) for potential therapeutic intervention in pancreatic cancer and other cancers as well as test novel kinase inhibitors in combination with chemotherapy to combat drug resistance.
Office: National Institute of Environmental Health Sciences - RTP
Phone: (919) 541-3201
Pharmacokinetic behavior of environmental chemicals, mechanisms of action of toxicants including endocrine disruptors, and linking of real-world exposures to health effects.
Currently not taking student rotations
Office: EPA HSF Room 558
Phone: (919) 536-2152
Inhalation Toxicology, Respiratory System Innate Immunity, Aerosols, New and Emerging Tobacco Products, Mucociliary Transport, Gamma Scintigraphy, Advanced Cell Culture Methods, Biomedical Engineering, Scientific Outreach and Community Engagement.
Office: U.S. Environmental Protection Agency - 104 Mason Farm Road, Chapel Hill
Phone: (919) 843-8031
Molecular and mechanistic toxicology, primary and organotypic in vitro models, live cell imaging/fluorescent biosensors, redox dysfunction/oxidative stress, inhalation toxicology, translational research, in vitro to in vivo extrapolation, environmental and public health epigenetics.
Office: 1309 Kerr Hall
Phone: (919) 962-0095
Establishing quantitative methods for proteins associated with drug disposition, understanding factors influencing the disposition, pharmacokinetics, reactivity and potential toxicity of labile acyl glucuronide metabolites, the role of glucuronidation in intestinal toxicity of drugs and the modulation of drug glucuronidation by botanicals/herbal remedies.
Office: 104 Mason Farm Road
Phone: (919) 966-5445
Dr. Cavin Ward-Caviness uses high-dimensional ‘omics data and large cohorts to study two major research themes: 1) determination of the molecular mechanisms linking environmental exposures and adverse health and 2) identification of molecular and clinical factors which may increase sensitivity to environmental exposures.