Curriculum Member Profiles
Office: 2253 Mary M. Townes Science Building - NCCU
Phone: (919) 530-6542
Validate novel molecular targets (ex. oncogenic PIM kinases) for potential therapeutic intervention in pancreatic cancer and other cancers as well as test novel kinase inhibitors in combination with chemotherapy to combat drug resistance.
Office: U.S. Environmental Protection Agency - 104 Mason Farm Road, Chapel Hill
Phone: (919) 843-8031
Molecular and mechanistic toxicology, primary and organotypic in vitro models, live cell imaging/fluorescent biosensors, redox dysfunction/oxidative stress, inhalation toxicology, translational research, in vitro to in vivo extrapolation, environmental and public health epigenetics.
Office: 1309 Kerr Hall
Phone: (919) 962-0095
Establishing quantitative methods for proteins associated with drug disposition, understanding factors influencing the disposition, pharmacokinetics, reactivity and potential toxicity of labile acyl glucuronide metabolites, the role of glucuronidation in intestinal toxicity of drugs and the modulation of drug glucuronidation by botanicals/herbal remedies.
Office: 104 Mason Farm Road
Phone: (919) 966-5445
Dr. Cavin Ward-Caviness uses high-dimensional ‘omics data and large cohorts to study two major research themes: 1) determination of the molecular mechanisms linking environmental exposures and adverse health and 2) identification of molecular and clinical factors which may increase sensitivity to environmental exposures.