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Hepatobiliary xenobiotic disposition, hepatotoxicity and pharmacokinetics

Institution: University of North Carolina Eshelman School of Medicine



Voice: (919) 962-7030


Research in the Brouwer laboratory is focused on: (1) hepatobiliary xenobiotic disposition, including mechanisms of hepatic uptake, translocation and biliary excretion; (2) development/refinement of in vitro model systems to predict in vivo hepatobiliary disposition, drug interactions, and hepatotoxicity; (3) hepatic drug transport; and (4) pharmacokinetics, including aberrant gastrointestinal drug absorption phenomena.