The Gordon Research Conference/Seminar in Cellular and Molecular Mechanisms of Toxicity took place in Andover, NH on August 9-14th, 2015 (https://www.grc.org/programs.aspx?id=14898). This conference showcased state-of-the-art mechanistic toxicological research. Topics included areas such as emerging technologies in basic, mechanistic, systems biology, epigenetics, the microbiome, and stem cells as well as computational, 3D, and in vivo modeling to assess toxicity. The Gordon Research Seminar (GRS) precedes the conference and provides trainees and young scientists with an opportunity to present their research and network in a relaxed environment (https://www.grc.org/programs.aspx?id=15534). In addition, the GRS includes career development sessions with panelists from industry, government, and academia who provide advice and constructive feedback on the interviewing process, effective CV and coverletter writing, as well as the different job sectors. This session was chaired by Dr. Rhiannon Hardwick, a former postdoc with the Curriculum in Toxicology. Six current PhD students from the UNC-CH Curriculum in Toxicology (Emma Bowers, Phil Wages, Dana Walsh, Leah Norona, Katelyn Lavrich, and Natalie Holman) submitted abstracts on their research. Of these six students, five were selected from all applicants around the world to give short oral presentations and all of them presented posters. A special congratulation goes out to Natalie Holman and Phil Wages, who won first and second place, respectively, for their excellent platform presentations.