{"id":3816,"date":"2019-10-16T20:18:20","date_gmt":"2019-10-17T00:18:20","guid":{"rendered":"https:\/\/www.med.unc.edu\/toxicology\/?post_type=directory&#038;p=3816"},"modified":"2023-09-06T15:05:30","modified_gmt":"2023-09-06T19:05:30","slug":"james-samet","status":"publish","type":"directory","link":"https:\/\/www.med.unc.edu\/toxicology\/directory\/james-samet\/","title":{"rendered":"James Samet"},"content":{"rendered":"<p><strong>Institution:<\/strong><\/p>\n<p><a class=\"external-link\" href=\"http:\/\/www.epa.gov\/nheerl\">U.S. Environmental Protection Agency<\/a><\/p>\n<p><strong>About:<\/strong><\/p>\n<p>Our laboratory is focused on the cellular and molecular mechanisms that control inflammatory and adaptive responses induced by inhalation of ambient air pollutants. Projects focus on early events that result in the disregulation of signaling processes that regulate gene expression, specifically oxidative effects that disrupt signaling quiescence in human lung cells. Approaches include live-cell imaging of human lung cells exposed in vitro and ex-vivo and characterization of oxidative protein modifications.<\/p>\n<p><a href=\"https:\/\/sph.unc.edu\/adv_profile\/james-samet\/\"><strong>Website<\/strong><\/a><\/p>\n<p><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/sites\/entrez?Db=pubmed&amp;Cmd=DetailsSearch&amp;Term=Samet,+James[Full+Author+Name]\"><strong>Publications<\/strong><\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Institution: U.S. Environmental Protection Agency About: Our laboratory is focused on the cellular and molecular mechanisms that control inflammatory and adaptive responses induced by inhalation of ambient air pollutants. Projects focus on early events that result in the disregulation of signaling processes that regulate gene expression, specifically oxidative effects that disrupt signaling quiescence in human &hellip; <a href=\"https:\/\/www.med.unc.edu\/toxicology\/directory\/james-samet\/\" aria-label=\"Read more about James Samet\">Read more<\/a><\/p>\n","protected":false},"featured_media":3817,"template":"","meta":{"_acf_changed":false,"_links_to":"","_links_to_target":""},"class_list":["post-3816","directory","type-directory","status-publish","has-post-thumbnail","hentry","odd"],"acf":[],"_upd_display_name":["James Samet"],"_upd_reverse_display_name":["Samet, James"],"_upd_last_name":["Samet"],"_upd_first_name":["James"],"_upd_sortorder_override":[],"_upd_sortorder":["1"],"_upd_gallery_summary":["<strong>Office:<\/strong> 145 Medical Drive <strong>| Phone:<\/strong> (919) 966-0665 <strong>| <a href=\"mailto:samet.james@epa.gov\">Email<\/a><\/strong>\r\n\r\nPrime Focus: Cell and molecular mechanisms of inflammatory responses induced by inhalation of ambient air pollutants."],"_upd_no_link":[],"_upd_degree1":["PhD"],"_upd_degree2":[],"_upd_email":[[{"email_text":"samet.james@epa.gov"}]],"_upd_phone":[[{"phone_text":"(919) 966-0665","phone_type":"Office Phone"}]],"_upd_address":[[{"address":{"address-1":"145 Medical Drive","address-2":"","campus-box":"","city":"Chapel Hill","state":"NC","zip":"27599"}}]],"_links":{"self":[{"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/directory\/3816","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/directory"}],"about":[{"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/types\/directory"}],"version-history":[{"count":0,"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/directory\/3816\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/media\/3817"}],"wp:attachment":[{"href":"https:\/\/www.med.unc.edu\/toxicology\/wp-json\/wp\/v2\/media?parent=3816"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}