{"id":2374,"date":"2012-02-13T20:05:00","date_gmt":"2012-02-14T01:05:00","guid":{"rendered":"https:\/\/www.med.unc.edu\/toxicology\/about-us\/member-profiles\/madden\/"},"modified":"2019-01-15T12:33:17","modified_gmt":"2019-01-15T17:33:17","slug":"madden","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/toxicology\/about-us\/madden\/","title":{"rendered":"Michael Madden"},"content":{"rendered":"<p><!-- description --><\/p>\n<p class=\"lead\">Physiology, Toxicology, Translational Medicine<\/p>\n<div>\n<p>Institution: <a class=\"external-link\" href=\"http:\/\/www.epa.gov\/nheerl\">U.S. Environmental Protection Agency<\/a><\/p>\n<p>Email: <a class=\"mail-link\" href=\"mailto:madden.michael@epa.gov\">madden.michael@epa.gov<\/a><\/p>\n<p>Voice: (919) 966-6257<\/p>\n<p><a class=\"external-link\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/sites\/entrez?Db=pubmed&amp;Cmd=DetailsSearch&amp;Term=Madden+MC[Author]\">Publications<\/a><\/p>\n<p>Exposure to ambient air particulate matter(PM) has been associated with increased human deaths and cardiopulmonary morbidity, such as lung infections and increased asthma symptoms. I am investigating some types of PM and associated gases (such as aldehydes) that may be associated with those health effects so that the US EPA may be able to better regulate or manage the sources of the PM that are identified as playing a role in the adverse health outcomes. I am currently focusing on the effects of diesel exhaust using a variety of approaches ranging from exposing cultured human cells to the exhaust, to studying responses of humans exposed out in traffic. The EPA rules for diesel exhaust from large trucks implemented in 2007 and 2010 will drastically change the type of emissions, and I am currently designing and implementing testing strategies to assess the toxicity of the future types of diesel emissions. Additionally some of my research effort attempts to identify what populations are more sensitive to the effects of air pollutants, and the genetic and environmental reasons behind the increased sensitivity.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Physiology, Toxicology, Translational Medicine Institution: U.S. Environmental Protection Agency Email: madden.michael@epa.gov Voice: (919) 966-6257 Publications Exposure to ambient air particulate matter(PM) has been associated with increased human deaths and cardiopulmonary morbidity, such as lung infections and increased asthma symptoms. I am investigating some types of PM and associated gases (such as aldehydes) that may be &hellip; <a href=\"https:\/\/www.med.unc.edu\/toxicology\/about-us\/madden\/\" aria-label=\"Read more about Michael Madden\">Read more<\/a><\/p>\n","protected":false},"author":315,"featured_media":0,"parent":2216,"menu_order":38,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2374","page","type-page","status-publish","hentry","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Michael Madden - Curriculum in Toxicology &amp; Environmental Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/toxicology\/about-us\/madden\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Michael Madden - Curriculum in Toxicology &amp; Environmental Medicine\" \/>\n<meta property=\"og:description\" content=\"Physiology, Toxicology, Translational Medicine Institution: U.S. Environmental Protection Agency Email: madden.michael@epa.gov Voice: (919) 966-6257 Publications Exposure to ambient air particulate matter(PM) has been associated with increased human deaths and cardiopulmonary morbidity, such as lung infections and increased asthma symptoms. I am investigating some types of PM and associated gases (such as aldehydes) that may be &hellip; Read more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.med.unc.edu\/toxicology\/about-us\/madden\/\" \/>\n<meta property=\"og:site_name\" content=\"Curriculum in Toxicology &amp; Environmental Medicine\" \/>\n<meta property=\"article:modified_time\" content=\"2019-01-15T17:33:17+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.med.unc.edu\/toxicology\/about-us\/madden\/\",\"url\":\"https:\/\/www.med.unc.edu\/toxicology\/about-us\/madden\/\",\"name\":\"Michael Madden - Curriculum in Toxicology &amp; Environmental Medicine\",\"isPartOf\":{\"@id\":\"https:\/\/www.med.unc.edu\/toxicology\/#website\"},\"datePublished\":\"2012-02-14T01:05:00+00:00\",\"dateModified\":\"2019-01-15T17:33:17+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.med.unc.edu\/toxicology\/about-us\/madden\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.med.unc.edu\/toxicology\/about-us\/madden\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.med.unc.edu\/toxicology\/about-us\/madden\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.med.unc.edu\/toxicology\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Private: About Us\",\"item\":\"https:\/\/www.med.unc.edu\/toxicology\/?page_id=2216\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Michael Madden\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.med.unc.edu\/toxicology\/#website\",\"url\":\"https:\/\/www.med.unc.edu\/toxicology\/\",\"name\":\"Curriculum in Toxicology &amp; Environmental Medicine\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.med.unc.edu\/toxicology\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Michael Madden - Curriculum in Toxicology &amp; Environmental Medicine","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.med.unc.edu\/toxicology\/about-us\/madden\/","og_locale":"en_US","og_type":"article","og_title":"Michael Madden - Curriculum in Toxicology &amp; Environmental Medicine","og_description":"Physiology, Toxicology, Translational Medicine Institution: U.S. Environmental Protection Agency Email: madden.michael@epa.gov Voice: (919) 966-6257 Publications Exposure to ambient air particulate matter(PM) has been associated with increased human deaths and cardiopulmonary morbidity, such as lung infections and increased asthma symptoms. 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