When NFL Hall of Famer and University of Colorado football coach Deion Sanders shared his recent diagnosis of bladder cancer, his story quickly made national headlines. In a feature published by MedPage Today (read the full article here), Sanders spoke candidly about his diagnosis, treatment, and recovery — and encouraged others to prioritize early detection through regular checkups.
The article included commentary from UNC Lineberger Comprehensive Cancer Center’s Matthew Milowsky, MD, Section Chief for Genitourinary Oncology, Co-Director of the Lineberger Urologic Oncology Program, and Adjunct Faculty for UNC Urology.
Dr. Milowsky noted that Sanders’ diagnosis — described by his surgeon as very high-risk non-muscle-invasive bladder cancer — can present complex treatment decisions. While some lower-risk cases may be managed with intravesical therapy, Dr. Milowsky explained that “in patients with very high-risk features, cystectomy can be preferred,” citing possible factors such as involvement of the prostatic urethra or lymphovascular invasion.
He also emphasized that urinary reconstruction following bladder removal is not one-size-fits-all. While Sanders underwent creation of a neobladder, Dr. Milowsky acknowledged that some patients opt for an ileal conduit, finding that the external collection device can reduce concerns and challenges associated with learning to manage a reconstructed bladder.
This national spotlight underscores Dr. Milowsky’s role as a trusted voice in urologic oncology and reflects UNC’s ongoing contributions to advancing expert, patient-centered care for bladder cancer.