{"id":4264,"date":"2018-07-27T09:00:34","date_gmt":"2018-07-27T13:00:34","guid":{"rendered":"https:\/\/www.med.unc.edu\/urology\/?p=4264"},"modified":"2018-08-03T09:47:46","modified_gmt":"2018-08-03T13:47:46","slug":"discovery-of-kidney-cancer-driver-could-lead-to-new-treatment-strategy","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/urology\/discovery-of-kidney-cancer-driver-could-lead-to-new-treatment-strategy\/","title":{"rendered":"Discovery of Kidney Cancer Driver Could Lead to New Treatment Strategy"},"content":{"rendered":"
\"\"
UNC Lineberger’s Qing Zhang, PhD, an assistant professor in the UNC School of Medicine Department of Pathology & Laboratory Medicine and Pharmacology.<\/figcaption><\/figure>\n

July 19, 2018\u00a0– In a study recently published in the journal Science, researchers led by UNC Lineberger’s<\/a> Qing Zhang, Ph.D., suggest that a protein, ZHX2, is a potential target for new therapeutic treatments for Clear Cell Renal Cell Carcinoma; the most common type of kidney cancer.<\/p>\n

(Learn More About Kidney Cancer)<\/a><\/h4>\n

More than 90% of the common kidney cancers have a genetic change that results in the loss of an important tumor suppressor called VHL. In this study, researchers were able to identify a new downstream effect of this genetic change that is driving kidney cancer growth. The findings of this research suggest that ZHX2 could therefore potentially be targeted by newer therapeutic treatments.<\/p>\n

UNC Lineberger\u2019s William Kim, MD, said there have been major advances in the treatment of kidney cancer with the development of molecularly-targeted therapies and immune-based treatments. However, additional treatments are needed to reach more patients with metastatic disease.<\/p>\n

Learn more about the research performed by UNC Lineberger’s Qing Zhang, Ph.D.<\/a><\/h4>\n","protected":false},"excerpt":{"rendered":"

July 19, 2018\u00a0– In a study recently published in the journal Science, researchers led by UNC Lineberger’s Qing Zhang, Ph.D., suggest that a protein, ZHX2, is a potential target for new therapeutic treatments for Clear Cell Renal Cell Carcinoma; the most common type of kidney cancer. (Learn More About Kidney Cancer) More than 90% of … Read more<\/a><\/p>\n","protected":false},"author":79967,"featured_media":4265,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-4264","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","odd"],"acf":[],"yoast_head":"\nDiscovery of Kidney Cancer Driver Could Lead to New Treatment Strategy | Department of Urology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.med.unc.edu\/urology\/discovery-of-kidney-cancer-driver-could-lead-to-new-treatment-strategy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Discovery of Kidney Cancer Driver Could Lead to New Treatment Strategy | Department of Urology\" \/>\n<meta property=\"og:description\" content=\"July 19, 2018\u00a0– In a study recently published in the journal Science, researchers led by UNC Lineberger’s Qing Zhang, Ph.D., suggest that a protein, ZHX2, is a potential target for new therapeutic treatments for Clear Cell Renal Cell Carcinoma; the most common type of kidney cancer. 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