{"id":8182,"date":"2020-07-29T13:56:23","date_gmt":"2020-07-29T17:56:23","guid":{"rendered":"https:\/\/www.med.unc.edu\/urology\/?p=8182"},"modified":"2020-07-31T10:37:00","modified_gmt":"2020-07-31T14:37:00","slug":"drs-bjurlin-fry-and-kim-awarded-lineberger-innovation-award-for-evaluating-the-carcinogenic-effects-of-e-cigarettes-on-the-urothelium","status":"publish","type":"post","link":"https:\/\/www.med.unc.edu\/urology\/drs-bjurlin-fry-and-kim-awarded-lineberger-innovation-award-for-evaluating-the-carcinogenic-effects-of-e-cigarettes-on-the-urothelium\/","title":{"rendered":"Drs. Bjurlin, Fry, and Kim Awarded Lineberger Innovation Award for Evaluating the Carcinogenic Effects of E-Cigarettes on the Urothelium"},"content":{"rendered":"<p class=\"lead\">Congratulations to\u00a0<a href=\"https:\/\/www.med.unc.edu\/urology\/directory\/marc-bjurlin-do\/\" rel=\"noopener\">Marc Bjurlin, DO, MSc, FACOS<\/a>, along with co-investigators Drs.\u00a0<a href=\"https:\/\/sph.unc.edu\/adv_profile\/rebecca-fry-phd\/\" target=\"_blank\" rel=\"noopener noreferrer\">Rebecca Fry,<\/a>\u00a0and\u00a0<a href=\"https:\/\/unclineberger.org\/directory\/william-y-kim\/\" target=\"_blank\" rel=\"noopener noreferrer\">William Kim<\/a>\u00a0on their recent <a href=\"#dev-funding\">UNC Lineberger Innovation Award<\/a> for \u201c<i>Evaluating the carcinogenic effects of electronic cigarettes on the urothelium.<\/i>\u201d This award will fund a pilot study starting this August for one full year &#8211; further extending Dr. Bjurlin&#8217;s body of work researching the dangers of e-cigarette usage.<\/p>\n<p class=\"lead\">This past fall, as part of\u00a0<a href=\"https:\/\/www.med.unc.edu\/urology\/funding-approved-for-pilot-analysis-of-bladder-carcinogens-in-the-urine-of-young-adult-e-cigarettes-users\/\">a multidisciplinary study<\/a>\u00a0funded through the NC TraCS and NYU, Dr. Bjurlin has been investigating the types of bladder cancer-causing biomarkers found in the urine of e-cigarette users.<\/p>\n<script>\n\n    (function($) {\n        $(\"body, html\").addClass(\"heels_full_width_overflow\");\n    })(jQuery);\n\n   <\/script>\n   <div style=\"background-color:#4b9cd3;\" class=\"full-width-contained whitebackground \">\n<div class=\"row  oscitas-bootstrap-container\">\n<div class=\"col-lg-9 col-md-8 col-xs-12 col-sm-6 oscitas-bootstrap-container\">\n<blockquote style=\"border-left: 5px solid #ffffff;\">\n<p class=\"lead\" style=\"color: #ffffff;\">&#8220;Given the large and increasing use of e-cigarettes, especially among youth, there is a pressing need to understand the health implications of vaping. Our study will evaluate the changes that take place in the bladder among e-cigarettes users as it pertains to bladder cancer risk.&#8221;<\/p>\n<h3 style=\"text-align: right; color: #ffffff; link-decoration: none;\"><a class=\"white\" href=\"https:\/\/www.med.unc.edu\/urology\/directory\/marc-bjurlin-do\/\">Marc Bjurlin, DO, MSc, FACOS<\/a><br \/>\nAssociate Professor of Urology<\/h3>\n<\/blockquote>\n<\/div>\n<div class=\"col-lg-3 col-md-4 col-xs-12 col-sm-6 oscitas-bootstrap-container\">\n<a href=\"https:\/\/www.med.unc.edu\/urology\/directory\/marc-bjurlin-do\/\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.med.unc.edu\/urology\/wp-content\/uploads\/sites\/637\/2018\/10\/Bjurlin-300x300.jpg\" alt=\"Marc Bjurlin, DO, MSc,\" width=\"300\" height=\"300\" class=\"alignnone size-medium wp-image-4410\" srcset=\"https:\/\/www.med.unc.edu\/urology\/wp-content\/uploads\/sites\/637\/2018\/10\/Bjurlin-300x300.jpg 300w, https:\/\/www.med.unc.edu\/urology\/wp-content\/uploads\/sites\/637\/2018\/10\/Bjurlin-150x150.jpg 150w, https:\/\/www.med.unc.edu\/urology\/wp-content\/uploads\/sites\/637\/2018\/10\/Bjurlin-768x768.jpg 768w, https:\/\/www.med.unc.edu\/urology\/wp-content\/uploads\/sites\/637\/2018\/10\/Bjurlin-600x600.jpg 600w, https:\/\/www.med.unc.edu\/urology\/wp-content\/uploads\/sites\/637\/2018\/10\/Bjurlin-560x560.jpg 560w, https:\/\/www.med.unc.edu\/urology\/wp-content\/uploads\/sites\/637\/2018\/10\/Bjurlin.jpg 1000w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/div>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<h2>Scientific Abstract<\/h2>\n<p>Electronic cigarette (e-cigarette) use is a public health crisis in the United States, with an exponential rise in its use over the last three years. E-cigarettes are considered an alternative to conventional cigarettes and their appealing appearance, taste and use characteristics make them popular among many age groups. Similar to combustible tobacco smokers, e-cigarette users are exposed to a variety of toxic and carcinogenic compounds during the vaping process. Specifically, carcinogenic compounds as well as their metabolized byproducts have been observed in the urine of e-cigarette users that have a strong link to the development of bladder cancer. Cigarette smoking produces specific bladder carcinogens which get converted into reactive intermediates that interact with DNA and have potential mutagenic consequences. We hypothesize that genomic events occur in e-cigarette users which may place them at risk for the development of bladder cancer and will assess e-cigarette users for these genomic events in an attempt to assist the understanding of potential bladder cancer risk of e-cigarette use.<\/p>\n<h2>UNC Lineberger Developmental Funding Program<\/h2>\n<p><a name=\"dev-funding\"><\/a>The UNC Lineberger <a href=\"https:\/\/unclineberger.org\/developmental-funding-opportunities\/\" target=\"_blank\" rel=\"noopener noreferrer\">Developmental Funding Program<\/a>\u00a0supports the innovation of cancer research led by faculty of the University of North Carolina at Chapel Hill and stimulates new applications for extramural funding.<\/p>\n<p>There are two rounds of funding supported each year, falling into two tiers of awards:\u00a0<strong><a target=\"_blank\" href=\"https:\/\/unclineberger.org\/developmental-funding-opportunities\/tier-1-pilot-awards\/\" rel=\"noopener noreferrer\">Tier 1: Pilot Awards<\/a><\/strong>\u00a0and\u00a0<strong><a target=\"_blank\" href=\"https:\/\/unclineberger.org\/developmental-funding-opportunities\/tier-2-stimulus-awards\/\" rel=\"noopener noreferrer\">Tier 2: Stimulus Awards<\/a><\/strong>. Within each tier, proposals are accepted in basic, clinical\/translational, and population science.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Congratulations to Marc Bjurlin, MD along with co-investigators Drs. Rebecca Fry, and William Kim, MD on their recent UNC Lineberger Innovation Award for \u201cEvaluating the carcinogenic effects of electronic cigarettes on the urothelium.\u201d<\/p>\n","protected":false},"author":79967,"featured_media":4410,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"layout":"","cellInformation":"","apiCallInformation":"","footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[63],"class_list":["post-8182","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","tag-bjurlin","odd"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Drs. 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