{"id":2219,"date":"2009-08-17T16:00:00","date_gmt":"2009-08-17T20:00:00","guid":{"rendered":"https:\/\/med.sites.unc.edu\/wolberglab\/scientific-images\/"},"modified":"2020-12-14T08:56:34","modified_gmt":"2020-12-14T13:56:34","slug":"scientific-images-2","status":"publish","type":"page","link":"https:\/\/www.med.unc.edu\/wolberglab\/scientific-images-2\/","title":{"rendered":"Scientific Images"},"content":{"rendered":"
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\"https:\/\/www.ahajournals.org\/cms\/asset\/7a589e2d-8698-4a45-aee4-b41c9a16823d\/atvbaha.120.314575.fig02.jpg\"<\/p>\n

von Willebrand Factor (VWF) Is not required for red blood cell retention in clots in mice (View publication<\/a>)<\/strong><\/p>\n

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\"Modifiers<\/p>\n

Modifiers of fibrin(ogen) and association with disease (<\/strong>View publication<\/strong><\/a>)<\/strong><\/p>\n

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\"FXIIIa<\/p>\n

FXIIIa cross-linking during fibrin formation (<\/strong>View publication<\/strong><\/a>)<\/strong><\/p>\n

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\"Venous<\/p>\n

Venous thrombi contain regions of high RBC and fibrin content (<\/strong>View publication<\/strong><\/a>)<\/strong><\/p>\n

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\"Interplay
\n Arterial thrombosis. <\/b><\/strong>Abbreviations: TM, thrombomodulin; II, prothrombin; IIa, thrombin; Fgn, fibrinogen; TF, tissue factor (View publication<\/a><\/strong>)<\/p>\n

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\"Tissue<\/p>\n

Schematic<\/a> of cell-mediated procoagulant activities leading to fibrin clot formation <\/b><\/p>\n

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\"Distribution
\nDistribution<\/a> of fibrin fibers above a cell surface (Laser Scanning Confocal Microscopy and Transmission Electron Microscopy)<\/b><\/p>\n

\"Normal<\/p>\n

Confocal micrographs of normal vs. hemophilic clots (<\/b>View publication<\/a>)<\/strong><\/p>\n

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\"Networks<\/a><\/p>\n

Scanning electron micrographs of networks formed under flow (left) and stasis (right) (<\/b>View publication<\/a>)<\/strong><\/p>\n

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Fibrinogen synthesis and expression (<\/strong>View publication<\/strong><\/a>)<\/strong><\/p>\n

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Contributions of FXIIIa to clot stability (<\/strong>View publication<\/a>)<\/strong><\/p>\n

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FXIIIa mediates RBC retention in thrombi (<\/strong>View publication<\/a>)<\/strong><\/p>\n

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\"\"
\nVenous thrombosis. <\/b>Abbreviations: TM, thrombomodulin; EPCR, endothelial protein C receptor; II, prothrombin; IIa, thrombin; TF, tissue factor; Fgn, fibrinogen; RBC, red blood cells (View publication<\/a>)<\/strong><\/p>\n

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Scanning electron micrograph of a whole blood clot<\/strong><\/p>\n

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\nTransmission electron micrographs of a whole blood clot<\/strong><\/p>\n

\"Contributions<\/p>\n

Virchow’s Triad (<\/b>View publication<\/strong><\/a>)<\/strong><\/p>\n

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\"Elevated<\/p>\n

Effects of elevated fibrinogen on thrombus development in carotid artery (left) and saphenous vein (right)<\/strong>
\n(View publication<\/a>)<\/strong><\/p>\n<\/div>\n<\/div>\n

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