Imaging Cognitive Reserve

BRIC Seminar Series Presenter: Yaakov Stern, Ph.D. Professor, Department of Neurology Columbia University College of Physicians and Surgeons

When Jan 08, 2014
from 01:00 PM to 02:00 PM
Where 1131 Bioinformatics
Contact Name
Contact Phone 919-966-4397
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Abstract
The concept of reserve arose from the mismatch between the extent of brain changes or pathology and the clinical manifestations of these brain changes. The cognitive reserve hypothesis posits that individual differences in the flexibility and adaptability of brain networks underlying cognitive function may allow some people to cope better with changes than others. Although there is ample epidemiologic evidence for cognitive reserve, the neural substrate of reserve is still a topic of ongoing research. I will review the concept and theory of reserve and describe our approach to investigating its neural implementation. I will present some representative studies from our group that exemplify possibilities for the neural substrate of reserve including neural reserve, neural compensation, and generalized cognitive reserve networks.

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