HTSF is closed for most research

As per directive from the Office of Vice Chancellor for Research, HTSF is only allowed to accept “critical research activities” listed below:

  1. Activities that are directly related to COVID-19
  2. Clinical trials requiring critical patient notification

For projects meeting these criteria, we will ask you to provide additional information. Contact the customer service staff for the Critical Research Form. HTSF will review your request and confirm with you if we will be able to accept you samples as a Critical Research Activity. In addition to the information you supply, we will have to consider staffing and availability of supplies in the approval process.

We will be electronically accepting routine samples. We have a secure way for samples to be dropped off at this time. Directions will be sent with Tracseq acceptance emails. The samples will be checked in and placed in our freezer system, but no work will proceed until UNC directives are loosen on what HTSF can process.

The HTSF managers and directors will continue to be here to answer questions/concerns, have conference calls and zoom meetings.
We regret the delays and inconvenience this exceptional circumstance has caused. We are reviewing our ability to reopen on a weekly basis. Determinations will be taking UNC directives and COVID19 status in to consideration. We will send emails, post on the HTSF website and Tracseq system any updates. Please be assured that as soon as we can we will be up running at full apacity and processing samples as quickly as we can.

Thank you for working with us in this ever changing situation
The HTSF Staff


Welcome to the High Throughput Genomic Sequencing Facility


History and Mission

The HTSF was established in 2008 with funds from the University Cancer Research Fund (UCRF) and the Lineberger Comprehensive Cancer Center (LCCC) and is managed by the UNC School of Medicine.

Our primary goal is to apply the tools of high throughput sequencing technology and experience to enrich medicine and basic biological research at The University of North Carolina. High-throughput sequencing is an extremely fast developing technology that is used to extract genetic and genomic data from a broad spectrum of biological materials. This information is not only be used to help identify the causes of complex diseases such as cancer, diabetes and cardiovascular disease and demonstrate the underlying bases for multiple types of infectious diseases.  It can be also used to analyze the complexities of diverse biological systems. Our goal is to support UNC researchers, students, and their collaborators in their work with our state-of-the-art technology to make medical and scientific breakthroughs happen.

We support all commercially available high throughput sequencing platforms and regularly work with researchers to develop and implement novel cutting edge applications with these platforms. We frequently work directly with the developers of new systems as an early access customer to give them useful feedback and to give our researchers the earliest possible access to novel new technologies.