Integrating Expertise, Enabling Data Driven Discovery, Informing Patient Care
Announcements
WELCOME TO THE HTSF SUBMISSION SYSTEM
We are open for all materials’ submission as Library Prep group and Sequencing group continue processing. If you already have an account at the HTSF, submit as needed. The Customer Service group will approve submission and work with you for drop off of the samples. Due to SOM COVID rules, we are scheduling 30m windows for drop off to insure social distancing for the lab and studies.
We continue to meet with studies for consults via zoom. Please reach out to customer service team with a brief description of your needs and we will help arrange a consult. If you have submission batch status questions, please reach out to the customer service staff.
We look forward to working with you.
Thank you
The HTSF Team
Director’s Welcome
Corbin Jones
We are pleased to have the opportunity to collaborate with you and support your research needs. The team is committed to providing the highest quality genomics and sequencing solutions, tailored to provide you the data you need to succeed, as cost effectively as possible. The HTSF have a long history in supporting research and scientific breakthroughs, and in helping understand a wide range of diseases and pathogens. We work with numerous vendors as beta testing sites for new services. Our R&D group can apply existing techniques in novel manners or help trouble shoot assays for you.
– Corbin Jones
Greg Bowen
– Greg Bowen
What’s New
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NovaSeq 6000 vs HighSeq 2500, Evaluation by mRNA-seq
This is a presentation on the comparison of the same series of libraries run on both the HS2500 and the Novaseq. These were TruSeq stranded mRNA. Pools of 4 libraries were run on the HiSeq 2500/ paired end/ 50x. The same pools were then pooled into larger pools (pools of pools) to be run on … Continued
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Scientific Highlight – Mammary Tumor Models
By creating new mammary tumor models, we find that tumor mutation burden and specific immune cells are associated with response. The core generated both single cell and bulk RNA-seq gene expression data to help this team of Lineberger researchers identify mechanisms mediating responses to immune checkpoint inhibitors using mouse models of triple-negative breast cancer. Hollern … Continued