This is a presentation on the comparison of the same series of libraries run on both the HS2500 and the Novaseq. These were TruSeq stranded mRNA. Pools of 4 libraries were run on the HiSeq 2500/ paired end/ 50x. The same pools were then pooled into larger pools (pools of pools) to be run on … Read more

By creating new mammary tumor models, we find that tumor mutation burden and specific immune cells are associated with response. The core generated both single cell and bulk RNA-seq gene expression data to help this team of Lineberger researchers identify mechanisms mediating responses to immune checkpoint inhibitors using mouse models of triple-negative breast cancer. Hollern … Read more