Category: Publication

Tangi Smallwood (Brian Bennett lab) published an article titled “High-resolution genetic mapping in the diversity outbred mouse population identifies Apobec1 as a candidate gene for atherosclerosis” published in G3: Genes, Genomes, Genetics 4: 2353-2363. (Image: Mapping of significant hits on Chromosome 9 for plasma triglyceride levels; see paper for full...

Crystal Waters (Dale Ramsden lab) published an article titled “The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining” published in Nature Communications 5: 4286. (Image: Model for organization of enzymatic steps during NHEJ.) Please see our page on Publications by GMB Students for more.

Laura Tollini (Yanping Zhang lab) published an article titled “Regulation of p53 by Mdm2 E3 ligase function is dispensable in embryogenesis and development, but essential in response to DNA damage” published in Cancer Cell 26: 235-247. (Image: Mdm2:MdmX heterodimer regulation of p53.) Please see our page on Publications by GMB...

Glenn Wozniak (Brian Strahl lab) published an article titled “Catalysis-dependent stabilization of Bre1 fine-tunes Histone H2B ubiquitylation to regulation gene transcription” published in Genes and Development 28: 1647-1652. (Image: Model for Bre1 function.) Please see our page on Publications by GMB Students for more.

Matt Simon (Shawn Ahmed lab) published an article titled “Reduced insulin/IGF-1 signaling restores germ cell immortality to Caenorhabditis elegans Piwi mutants.” published in Cell Reports 7: 762-773. (Image: Changes in expression of tandem repeat loci, genome-wide.) Please see our page on Publications by GMB Students for more.

Bailey Peck (Praveen Sethupathy lab) is co-first author on an article titled “microRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes” published in Diabetes (published online ahead of print, April 2014). (Image: Schematic of the FOXA2:miR-29 regulatory circuit...

Jennifer Kulzer(Karen Mohlke lab) published a paper titled “A common functional regulatory variant at a type 2 diabetes locus upregulates ARAP1 expression in the pancreatic beta cell” in American Journal of Human Genetics (v. 94, pp 186-197). (Image: Association of SNPs with fasting proinsulin levels; see article for details.) Please...

Christian Parobek (Jon Juliano lab) published a paper titled “A multilocus microsatellite genotyping array to investigate the genetic epidemiology of Pneumocystis jirovecii” in Journal of Clinical Microbiology (published ahead of print Feb 12). (Image: Potential mutational paths from haplotypes from Uganda, Spain, and San Francisco.) Please see our page on...

Kate Hacker (Kim Rathmell lab) is co-first author on a paper titled “Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects” in Genome Research (v. 24, pp 241-250). (Image: H3K36me3 staining in clear cell renal carcinoma – normal kidney pairs; see article...

Jeffrey Damrauer (Billy Kim lab) published a paper titled “Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology” in Proceedings of the National Academy of Sciences, USA (v. 111, pp 3110-3115). (Image: proposed model of urothelial tumorigenesis; see article for details.)

Congratulations to Marta Charpentier (lab of Frank Conlon), first author of a publication in Developmental Cell, titled “CASZ1 promotes vascular assembly and morphogenesis through the direct regulation of an EGFL7/RhoA-mediated pathway.”  Marta’s work was featured as the cover image.

Congratulations to Kathryn Kohl for the recent publication of their paper in Science entitled “Evolution of an MCM Complex in Flies That Promotes Meiotic Crossovers by Blocking BLM Helicase”.