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Taylor Penke publishes paper in Genetics

November 19, 2017
Taylor Penke (Bob Duronio lab) published a paper titled “Functional redundancy of variant and canonical histone H3 lysine 9 modification in Drosophila“ in Genetics (DOI: 10.1534/genetics.117.300480). Image: Heterochromatin marks in polytene chromosomes from wild-type and Histone H3.3 mutants (null and K9R missense (see article for details). Please see our page...

Charlie Hodgens publishes paper in PLOS One

November 19, 2017
Charlie Hodgens (Joe Keiber lab) published a paper titled “indCAPS: A tool for designing screening primers for CRISPR/Cas9 mutagenesis events” in PLOS One (DOI: 10.1371/journal.pone.0188406). Image: A. thaliana seedlings imaged at 2.5 weeks of growth, showing phenotypes of CRISPR mutations in the cytokine gene AHK3 designed using the indCAPS tool....

Lauren Donoghue publishes paper in Genetics

October 2, 2017
Lauren Donoghue (Samir Kelada lab) published a paper titled “Identification of trans protein QTL for secreted airway mucins in mice and a causal role for Bpifb1” in Genetics (DOI: 10.1534/genetics.117.300211). Image: AB-PAS and MUC5B in airways of naïve or sensitized and challenged mice (click to enlarge); see article for details....

Talia Hatkevich publishes review in Bioessays

October 2, 2017
Talia Hatkevich (Jeff Sekelsky lab) published a Problems and Paradigms review titled “Bloom syndrome helicase in meiosis: Pro-crossover functions of an anti-crossover protein” in Bioessays (DOI: 10.1002/bies.201700073). Image: Model for Blm helicase in Drosophila meiosis. click to magnify; see article for details. Please see our page on Publications by GMB...

Jordan Kardos publishes paper in JCO Precision Oncology

July 12, 2017
Jordan Kardos (William Kim lab) published a paper titled “Comprehensive molecular characterization of urachal adenocarcinoma reveals commonalities with colorectal cancer, including a hypermutable phenotype” in JCO Precision Oncology (DOI: 10.1200/PO.17.00027). Image: Comparison of mutations per Mb in bladder, colorectal, and urachal cancers; see article for details. Please see our page...

Aleisha Smith publishes paper in Nature Communications

June 27, 2017
Aleisha Smith (William Kim lab) published a paper titled “MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma” in Nature Communications (DOI: 10.1038/ncomms15770). Former GMB student Sean Bailey is co-first author and Jordan Kardos is also an author. Image: Venn diagram of gene expression...

Chris Uyehara and Spencer Nystrom publish paper in Genes and Development

June 1, 2017
Chris Uyehara and Spencer Nystrom (Dan McKay lab) published a paper titled “Hormone-dependent control of developmental timing through regulation of chromatin accessibility” in Genes and Development (DOI: 10.1101/gad.298182.117). Matt Niederhuber was also an author. Image: Expression of nub in the developing wing; see article for details. Please see our page...

Josh Lawrimore publishes paper in Molecular Biology of the Cell

May 10, 2017
Josh Lawrimore (Kerry Bloom lab) published a paper titled “Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage” in Molecular Biology fo the Cell (DOI: 10.1091/mbc.E16-12-0846). Image: Positioning of the telomere (green) within the nucleus; see paper for details. Please see our page on Publications by...

John Noto publishes review in RNA Biology

May 9, 2017
John Noto (Greg Matera lab) published a review titled “Engineering and expressing circular RNAs via tRNA splicing“ in RNA Biology (DOI: 10.1080/15476286.2017.1317911). Image: In vivo RNA circularization pathways; see article for details. Please see our page on Publications by GMB Students for more.

Sarah Renner publishes paper in PLOS One

May 9, 2017
Sarah Renner (Jay Brenman lab) published a paper titled “Carbonic anhydrase III (Car3) is not required for fatty acid synthesis and does not protect against high-fat diet induced obesity in mice“ in PLOS One (DOI: 10.1371/journal.pone.0176502). Image: Alignment of cytosolic anhydrase sequences; see paper for details. Please see our page...

Joe Durand publishes chapter in Adv. Protein Chemistry & Structural Biol.

May 9, 2017
Joe Durand (Al Baldwin lab) published a chapter titled “Targeting IKK and NF-κB for Therapy“ in Advances in Protein Chemistry and Structural Biology: Chromatin Proteins and Transcription Factors as Therapeutic Targets (DOI: 10.1016/bs.apcsb.2016.11.006). Image: Canonical and non-canonical NF-κB pathways; see article for details. Please see our page on Publications by GMB...

Michaelyn Hartmann publishes review in Fly

May 5, 2017
Michaelyn Hartmann (Jeff Sekelsky lab) published an article titled “The absence of crossovers on chromosome 4 in Drosophila melanogaster: Imperfection or interesting exception?“ in Fly (DOI: 10.1080/19336934.2017.1321181). Image: Comparison of crossover rates on proximal 2L and 4; see article for details. Please see our page on Publications by GMB Students...