Frank L. Conlon, PhD
Professor
Areas of Interest
sex differences; cardiac; heart; proteomic; mouse models; stem cells; congenital heart disease; development; translational science; genetics; biochemistry; chromatin; transcription; RNA; translation; protein turnover
About
- Department Affiliations:
- Department of Biology; Department of Genetics
- Other UNC PhD Program Affiliations:
- Genetics; Cell Biology and Physiology; Biochemistry; Pathology; Biology
My Research
The work in our lab is focused on identifying the molecular networks that are essential for early heart development and how sex difference in these networks lead to sex disparities in heart disease. For these studies, we use a highly integrated approach that incorporates developmental, genetic, proteomic, biochemical and molecular based studies in mouse and stem cells.
Recent advances and projects of interest in the Conlon lab include studies that define the cellular and molecular events that lead to cardiac sex differences, those that explore cardiac interaction networks as determinants of transcriptional specificity, the mechanism and function of cardiac transcriptional repression networks, and the regulatory networks of cardiac morphogenesis.