Michael Emanuele, PhD
Professor
Areas of Interest
Cell cycle control, ubiquitin system, signaling, cancer, proliferation, CDK-RB pathway, therapeutics, proteomics, mass spectrometry, systems biology,
About
My Research
Our lab studies the role of ubiquitin signaling in cell cycle control and cancer proliferation. Using advanced methods in proteomics we map ubiquitin signaling networks at unprecedented depth, and then leverage these systems level data to address two fundamental questions. First, how do specific enzymes contribute to cell cycle and proliferation, and second, and how these signaling dynamics might y influenced by cancer progression or in response to disease treatment.