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MHI SEMINAR SERIES: Mingfu Wu, Ph.D., Associate Professor, Pharmacology, Department of Pharmacological and Pharmaceutical Sciences, University of Houston

Pagano Conference Room, #00-002, Lineberger Comprehensive Cancer Center 450 West Drive, Chapel Hill, NC, United States

RESEARCH: My lab aims to determine the etiology and then the treatment for the left ventricular non-compaction cardiomyopathy. 2. Another project will determine how epicardial development regulates cardiac morphogenesis and explore methods to treat congenital heart defects caused by abnormal epicardial development. 3. We are also screening chemicals that promote cardiomyocyte maturation during cell-reprogramming and … Read more

MHI SEMINAR SERIES: Jonathan Brown, M.D., Associate Professor, Medicine, Cardiovascular Medicine at Vanderbilt University

Pagano Conference Room, #00-002, Lineberger Comprehensive Cancer Center 450 West Drive, Chapel Hill, NC, United States

Jonathan Brown, MD, is a cardiologist and basic scientist studying transcriptional mechanisms relevant to the pathogenesis of obesity, diabetes mellitus, and atherosclerosis. A central premise of his research involves a deeper understanding of the gene regulatory networks controlling disease pathogenesis to identify novel therapeutic targets to treat these prevalent and often fatal conditions. More specifically, … Read more

Rong Wang, Ph.D., Professor of Surgery, Director, Laboratory for Accelerated Vascular Research, UCSF

Pagano Conference Room, #00-002, Lineberger Comprehensive Cancer Center 450 West Drive, Chapel Hill, NC, United States

Research Overview: MOLECULAR PROGRAMMING OF THE VASCULATURE IN DEVELOPMENT AND DISEASE Proper formation and function of the vasculature are crucial for health and survival, as the vasculature supplies all cells in the body. A dysfunctional vasculature causes myriad diseases, including stroke, arterial occlusive diseases, and vascular anomalies. Our long-term goal is to identify novel drug … Read more

MHI SEMINAR SERIES: Karen Hirschi, Ph.D., Professor, Cell Biology, Director, UVA Developmental Genomics Center, University of Virginia

1131 Bioinformatics Building 130 Mason Farm Rd., Chapel Hill, NC, United States

Research Interest: Our laboratory is specifically interested in the regulation of endothelial cell commitment, differentiation and cell cycle progression, and defining signaling pathways that modulate these processes. We also aim to understand how some endothelial cells acquire specialized functions, such as the generation and/or maintenance of multi-lineage stem/progenitor cells.