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Sara Elizabeth Wobker, MD, MPH

Associate Professor Director of Surgical Pathology Director of Genitourinary Pathology

Research Interests

My research is focused on the clinical translational study of genitourinary cancers, with a particular interest in the molecular characterization of rare variants of bladder carcinoma.

Selected Publications

  1. Saunders KE, Cody Craig J, Hoerres DL, Maygarden SJ, Wobker SE. Less Is More: Evaluation of Gross Examination Protocol for Cystectomy Specimens Following Neoadjuvant Chemotherapy. Am J Clin Pathol. 2022 May 24:aqac064. Epub ahead of print. PMID: 35608539.
  2. Mirza KM, Gonzalez RS, Jiang XS, Khanafshar E, Wobker SE. Excellence Available Everywhere. Am J Clin Pathol. 2021 Oct 13;156(5):839-845. doi: 10.1093/ajcp/aqab029.  PMID: 33978152
  3. Damrauer JS, Roell KR, Smith MA, Sun X, Kirk EL, Hoadley KA, Benefield HC, Iyer G, Solit DB, Milowsky MI, Kim WY, Nielsen ME, Wobker SE, Dalbagni G, Al-Ahmadie HA, Olshan AF, Bochner BH, Furberg H, Troester MA, Pietzak EJ. Identification of a Novel Inflamed Tumor Microenvironment Signature as a Predictive Biomarker of Bacillus Calmette-Guérin Immunotherapy in Non-Muscle-Invasive Bladder Cancer. Clin Cancer Res. 2021 Aug 15;27(16):4599-4609. doi: 10.1158/1078-0432.CCR-21-0205. Epub 2021 Jun 11.PMID: 34117034
  4. Trpkov K, Hes O, Williamson SR, Adeniran AJ, Agaimy A, Alaghehbandan R, Amin MB, Argani P, Chen YB, Cheng L, Epstein JI, Cheville JC, Comperat E, da Cunha IW, Gordetsky JB, Gupta S, He H, Hirsch MS, Humphrey PA, Kapur P, Kojima F, Lopez JI, Maclean F, Magi-Galluzzi C, McKenney JK, Mehra R, Menon S, Netto GJ, Przybycin CG, Rao P, Rao Q, Reuter VE, Saleeb RM, Shah RB, Smith SC, Tickoo S, Tretiakova MS, True L, Verkarre V, Wobker SE, Zhou M, Gill AJ. New developments in existing WHO entities and evolving molecular concepts: The Genitourinary Pathology Society (GUPS) update on renal neoplasia. Mod Pathol. 2021 Jul;34(7):1392-1424. doi: 10.1038/s41379-021-00779-w. Epub 2021 Mar 4. PMID: 33664427
  5. Trpkov K, Williamson SR, Gill AJ, Adeniran AJ, Agaimy A, Alaghehbandan R, Amin MB, Argani P, Chen YB, Cheng L, Epstein JI, Cheville JC, Comperat E, da Cunha IW, Gordetsky JB, Gupta S, He H, Hirsch MS, Humphrey PA, Kapur P, Kojima F, Lopez JI, Maclean F, Magi-Galluzzi C, McKenney JK, Mehra R, Menon S, Netto GJ, Przybycin CG, Rao P, Rao Q, Reuter VE, Saleeb RM, Shah RB, Smith SC, Tickoo S, Tretiakova MS, True L, Verkarre V, Wobker SE, Zhou M, Hes O. Novel, emerging and provisional renal entities: The Genitourinary Pathology Society (GUPS) update on renal neoplasia. Mod Pathol. 2021 Jun;34(6):1167-1184. doi: 10.1038/s41379-021-00737-6. Epub 2021 Feb 1. PMID: 33526874.  Correction: in Mod Pathol. 2021 May;34(5):1037. doi: 10.1038/s41379-021-00775-0. PMID: 33727698.
  6. Fine SW, Trpkov K, Amin MB, Algaba F, Aron M, Baydar DE, Beltran AL, Brimo F, Cheville JC, Colecchia M, Comperat E, Costello T, da Cunha IW, Delprado W, DeMarzo AM, Giannico GA, Gordetsky JB, Guo CC, Hansel DE, Hirsch MS, Huang J, Humphrey PA, Jimenez RE, Khani F, Kong MX, Kryvenko ON, Kunju LP, Lal P, Latour M, Lotan T, Maclean F, Magi-Galluzzi C, Mehra R, Menon S, Miyamoto H, Montironi R, Netto GJ, Nguyen JK, Osunkoya AO, Parwani A, Pavlovich CP, Robinson BD, Rubin MA, Shah RB, So JS, Takahashi H, Tavora F, Tretiakova MS, True L, Wobker SE, Yang XJ, Zhou M, Zynger DL, Epstein JI. Practice patterns related to prostate cancer grading: results of a 2019 Genitourinary Pathology Society clinician survey. Urol Oncol. 2021 May;39(5):295.e1-295.e8. doi: 10.1016/j.urolonc.2020.08.027. Epub 2020 Sep 15. PMID: 32948433
  7. Epstein JI, Amin MB, Fine SW, Algaba F, Aron M,  Baydar DE, Beltran AL, Brimo F, Cheville JC, Colecchia M, Comperat E, da Cunha IW, Delprado W, DeMarzo AM, Giannico GA, Gordetsky JB, Guo CC, Hansel DE, Hirsch MS, Huang J, Humphrey PA, Jimenez RE, Khani F, Kong Q, Kryvenko ON, Kunju LP, Lal P, Latour M, Lotan T, Maclean F, Magi-Galluzzi C, Mehra R, Menon S, Miyamoto H, Montironi R, Netto GJ, Nguyen JK, Osunkoya AO, Parwani A, Robinson BD, Rubin MA, Shah RB, So JS, Takahashi H, Tavora F, Tretiakova MS, True L, Wobker SE, Yang XJ, Zhou M, Zynger DL, Trpkov K. The 2019 Genitourinary Pathology Society (GUPS) White Paper on Contemporary Grading of Prostate Cancer.  Arch Pathol Lab Med. 2021 Apr 1;145(4):461-493. doi: 10.5858/arpa.2020-0015-RA. Review. PMID: 32589068
  8. †Johnson SM, Khararjian A, Legesse TB, Khani F, Robinson BD, Epstein JI, Wobker SE. Nested Variant of Urothelial Carcinoma is a Luminal Bladder Tumor with Distinct Coexpression of the Basal Marker Cytokeratin 5/6. Am J Clin Pathol. 2021 Mar 15;155(4):588-596. doi: 10.1093/ajcp/aqaa160. PMID: 33118597
  9. Kardos J, Rose TL, Manocha U, Wobker SE, Damrauer JS, Bivalaqua TJ, Kates M, Moore KJ, Parker JS, Kim WY. Development and validation of a NanoString BASE47 bladder cancer gene classifier. PLoS One. 2020 Dec 17;15(12):e0243935. doi: 10.1371/journal.pone.0243935. eCollection 2020.  PMID: 33332422
  10. Manocha U, Kardos J, Selitsky S, Zhou M, Johnson SM, Breslauer C, Epstein JI, Kim WY, Wobker SE. RNA Expression Profiling of Lymphoepithelioma-Like Carcinoma of the Bladder Reveals a Basal-like Molecular Subtype. Am J Pathol. 2020 Jan;190(1):134-144. doi: 10.1016/j.ajpath.2019.09.007. Epub 2019 Oct 11. PMID: 31610173
  11. Wobker SE, Matoso A, Pratilas CA, Mangray S, Zheng G, Lin MT, Debeljak M, Epstein JI, Argani P. Metanephric Adenoma–Epithelial Wilms Tumor Overlap Lesions: An Analysis of BRAF Status. Am J Surg Pathol. 2019 Sep;43(9):1157-1169. doi: 10.1097/PAS.0000000000001240. PMID: 31192863

List of publications from PubMed