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4 years ago

New publication in Research and Practice in Thrombosis and Haemostasis “COVID-19 Pandemic Perspectives: A Scientific Silver Lining?”

New publication in Research and Practice in Thrombosis and Haemostasis “COVID-19 Pandemic Perspectives:  A Scientific Silver Lining?” Abstract Accounts of the numerous negative effects caused by COVID‐19 are pervasive, but few perspectives have identified any positive impacts of this massive societal shift. This forum examines potentially positive changes that have occurred within the scientific community …

4 years ago

New publication in Research and Practice in Thrombosis and Haemostasis

Factor XIII Deficiency Does Not Prevent FeCl3-induced Carotid Artery Thrombus Formation in Mice Background: The compositions of venous (red blood cell-rich) and arterial (platelet-rich) thrombi are mediated by distinct pathophysiologic processes; however, fibrin is a major structural component of both. The transglutaminase factor XIII (FXIII) stabilizes fibrin against mechanical and biochemical disruption and promotes red …

4 years ago

New publication in the Journal of Thrombosis and Haemostasis

The factor XIII‐A Val34Leu polymorphism decreases whole blood clot mass at high fibrinogen concentrations Background: Factor XIII (FXIII) promotes fibrin crosslinking and red blood cell (RBC) retention in clots. The FXIII‐A polymorphism, Val34Leu, is associated with protection against venous thrombosis. This effect is hypothesized to result from fibrinogen concentration‐dependent changes in fibrin structure. Effects of the …

 
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