Publications

Mouillesseaux, KP., Wiley, DS., Saunders, LM., Wylie, LA., Kushner, EJ., Chong, DC., Citrin, KM., Barber, AT., Park, Y., Kim, J., Samsa, LA., Kim, J., Liu, J., Jin, S., Bautch, VL. Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6. 2016. Nature Communications. 7:13247. DOI: 10.1038/ncomms13247

Chappell, JC, Mouillesseaux, KP, Bautch, VL. Flt-1 (Vascular Endothelial Growth Factor Receptor-1) Is Essential for the Vascular Endothelial Growth Factor–Notch Feedback Loop During Angiogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. 2013;33:1952–1959. https://doi.org/10.1161/ATVBAHA.113.301805

Wiley, DM., KimJ., Hao, J., Hong, CC., Bautch, VL., Jin, S. Distinct Signaling Pathways Regulate Sprouting Angiogenesis from the Dorsal Aorta and Axial Vein. Nat Cell Biol. 2011 June ; 13(6): 686–692. doi:10.1038/ncb2232.

Hyouk-Bum Kwon, Duncan I. Mackie, Remy Bonnavion, Alan Le Mercier, Christian S. M. Helker, Taekwon Son, Stefan Guenter, D. Stephen Serafin, Kyu-Won Kim, Stefan Offermanns, Kathleen M. Caron, and Didier Y. R. Stainier. The Orphan G-Protein Coupled Receptor 182 Is a Negative Regulator of Definitive Hematopoiesis through Leukotriene B4 Signaling. ACS Pharmacology & Translational Science. 2020, 3, 4, 676–689
DOI: 10.1021/acsptsci.0c00020

Estes, JM., Altemara, ML., Crim, MJ., Fletcher, CA., and Whitaker, JW. Behavioral and Reproductive Effects of Environmental Enrichment and Pseudoloma neurophilia infection on Adult Zebrafish (Danio rerio). 2021. JAALAS. Vol 60(3):249–258. DOI: 10.30802/AALAS-JAALAS-20-000113

Graves, CL, Norloff, E, Thompson, D, Kosyk, O, Sang, Y, Chen, A, Zannas, AS, Wallet, SM. Chronic early life stress alters the neuroimmune profile and functioning of the developing zebrafish gut, Brain, Behavior, & Immunity – Health, Volume 31, 2023, 100655, ISSN 2666-3546, https://doi.org/10.1016/j.bbih.2023.100655.

Dong Y*, Yang Y*, Wang H, Feng D, Nist E, Yapundich N, Spurlock B, Craft M, Qian L, Liu J. 2024. Single-cell chromatin profiling reveals genetic programs activating pro-regenerative states in non-myocyte cells. Sci Adv. (in press) (*co-first authors)

Ma H, Liu Z, Yang Y, Feng D, Dong Y, Garbutt TA, Hu Z, Wang L, Luan C, Cooper CD, Li Y, Welch JD, Qian L, Liu J. Functional coordination of non-myocytes plays a key role in adult zebrafish heart regeneration. EMBO Rep. 2021 Nov 4;22(11):e52901. doi: 10.15252/embr.202152901. Epub 2021 Sep 15. PMID: 34523214; PMCID: PMC8567231

Battista NA, Douglas DR, Lane AN, Samsa LA, Liu J, Miller LA. Vortex Dynamics in Trabeculated Embryonic Ventricles. J Cardiovasc Dev Dis. 2019 Jan 22;6(1):6. doi: 10.3390/jcdd6010006. PMID: 30678229; PMCID: PMC6463151.

Battista NA, Lane AN, Liu J, Miller LA. Fluid dynamics in heart development: effects of hematocrit and trabeculation. Math Med Biol. 2018 Dec 5;35(4):493-516. doi: 10.1093/imammb/dqx018. PMID: 29161412; PMCID: PMC7970531.

Fleming ND, Samsa LA, Hassel D, Qian L, Liu J. Rapamycin attenuates pathological hypertrophy caused by an absence of trabecular formation. Sci Rep. 2018 Jun 5;8(1):8584. doi: 10.1038/s41598-018-26843-1. PMID: 29872120; PMCID: PMC5988815.

Brown D, Samsa LA, Ito C, Ma H, Batres K, Arnaout R, Qian L, Liu J. Neuregulin-1 is essential for nerve plexus formation during cardiac maturation. J Cell Mol Med. 2018 Mar;22(3):2007-2017. doi: 10.1111/jcmm.13408. Epub 2017 Dec 19. PMID: 29265764; PMCID: PMC5824398.

Haskell GT, Jensen BC, Samsa LA, Marchuk D, Huang W, Skrzynia C, Tilley C, Seifert BA, Rivera-Muñoz EA, Koller B, Wilhelmsen KC, Liu J, Alhosaini H, Weck KE, Evans JP, Berg JS. whole exome sequencing identifies truncating variants in nuclear envelope genes in patients with cardiovascular disease. Circ Cardiovasc Genet. 2017 Jun;10(3):e001443. doi: 10.1161/CIRCGENETICS.116.001443. PMID: 28611029; PMCID: PMC5497793

Samsa LA, Ito CE, Brown DR, Qian L, Liu J. IgG-Containing isoforms of Neuregulin-1 are dispensable for cardiac trabeculation in zebrafish. PLoS One. 2016 Nov 15;11(11):e0166734. doi: 10.1371/journal.pone.0166734. PMID: 27846271; PMCID: PMC5112773.

Fleming, ND., Samsa, LA., Hassel, D., Qian, L., Liu, J. Rapamycin attenuates pathological
hypertrophy caused by an absence of trabecular formation. Scientific Reports (2018) 8:8584. DOI:10.1038/s41598-018-26843-1

Mouillesseaux KP, Wiley DS, Saunders LM, Wylie LA, Kushner EJ, Chong DC, Citrin KM, Barber AT, Park Y, Kim JD, Samsa LA, Kim J, Liu J, Jin SW, Bautch VL. Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6. Nat Commun. 2016 Nov 11;7:13247. doi: 10.1038/ncomms13247. PMID: 27834400; PMCID: PMC5114582.

Brown DR, Samsa LA, Qian L, Liu J. Advances in the study of heart development and disease using zebrafish. J Cardiovasc Dev Dis. 2016 Jun;3(2):13. doi: 10.3390/jcdd3020013. Epub 2016 Apr 9. PMID: 27335817; PMCID: PMC4913704.

Samsa LA, Fleming N, Magness S, Qian L, Liu J. Isolation and Characterization of Single Cells from Zebrafish Embryos. J Vis Exp. 2016 Mar 12;(109):53877. doi: 10.3791/53877. PMID: 27022828; PMCID: PMC4828977.

Samsa LA, Ito CE, Brown DR, Qian L, Liu J (2016) IgG-Containing Isoforms of Neuregulin-1 Are Dispensable for Cardiac Trabeculation in Zebrafish. PLoS ONE 11(11): e0166734. https://doi.org/10.1371/journal.pone.0166734

Samsa, L. A., Fleming, N., Magness, S., Qian, L., Liu, J. Isolation and Characterization of Single Cells from Zebrafish Embryos. J. Vis. Exp. (109), e53877, doi:10.3791/53877 (2016).

Samsa LA, Givens C, Tzima E, Stainier DY, Qian L, Liu J. Cardiac contraction activates endocardial Notch signaling to modulate chamber maturation in zebrafish. Development. 2015 Dec 1;142(23):4080-91. doi: 10.1242/dev.125724.

– Highlighted Research Article.

– Previewed by “Cilia: at the heart of chamber maturation” Development. 2015;142:e230.

Zou J, Tran D, Baalbaki M, Tang LF, Poon A, Pelonero A, Titus EW, Yuan C, Shi C, Patchava S, Halper E, Garg J, Movsesyan I, Yin C, Wu R, Wilsbacher LD, Liu J, Hager RL, Coughlin SR, Jinek M, Pullinger CR, Kane JP, Hart DO, Kwok PY, Deo RC. An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish. Elife. 2015 Oct 16;4:e09406. doi: 10.7554/eLife.09406. PMID: 26473617; PMCID: PMC4720518.

Staudt DW, Liu J, Thorn KS, Stuurman N, Liebling M, Stainier DY. High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation. Development. 2014 Feb;141(3):585-93. doi: 10.1242/dev.098632. Epub 2014 Jan 8. PMID: 24401373; PMCID: PMC3899815.

Samsa LA, Yang B, Liu J. Embryonic cardiac chamber maturation: Trabeculation, conduction, and cardiomyocyte proliferation. Am J Med Genet C Semin Med Genet. 2013 Aug;163C(3):157-68. doi: 10.1002/ajmg.c.31366. Epub 2013 May 29. PMID: 23720419; PMCID: PMC3723796.

Honeycutt SE, O’Brien LL. Injection of Evans blue dye to fluorescently label and image intact vasculature. Biotechniques. 2021 Mar;70(3):181-185. doi: 10.2144/btn-2020-0152. Epub 2020 Dec 18. PMID: 33337254; PMCID: PMC7983036.

Graves, CL.,1A. Chen, V. Kwon, CE. Shiau. (2021) Zebrafish harbor diverse intestinal macrophage populations including a subset intimately associated with enteric neural processes. iScience 24(6):25, 102496

Yang, L., Jiménez, J. A., Earley, A. M., Hamlin, V., Kwon, V., Dixon, C. T., & Shiau, C. E. (2020). Drainage of inflammatory macromolecules from the brain to periphery targets the liver for macrophage infiltration. eLife, 9, e58191. https://doi.org/10.7554/eLife.58191

Earley, AM., Graves, CL., Shiau, CE. Critical Role for a Subset of Intestinal Macrophages
in Shaping Gut Microbiota in Adult Zebrafish. 2018, Cell Reports 25, 424–436
doi.org/10.1016/j.celrep.2018.09.025

Earley AM, Dixon CT, Shiau CE (2018) Genetic analysis of zebrafish homologs of human FOXQ1, foxq1a and foxq1b, in innate immune cell development and bacterial host response. PLoS ONE 13(3): e0194207. https://doi.org/10.1371/journal.pone.0194207

Chrispell JD, Dong E, Osawa S, Liu J, Cameron DJ, Weiss ER. Grk1b and Grk7a Both Contribute to the Recovery of the Isolated Cone Photoresponse in Larval Zebrafish [published correction appears in Invest Ophthalmol Vis Sci. 2018 Nov 1;59(13):5670]. Invest Ophthalmol Vis Sci. 2018;59(12):5116–5124. doi:10.1167/iovs.18-24455

Chrispell, J.D., Rebrik, T.I., Weiss, E.R. Electroretinogram Analysis of the Visual Response in Zebrafish Larvae. J. Vis. Exp. (97), e52662, doi:10.3791/52662 (2015).

Evan M. Zeitler*, Yuanyuan Li*, Madison Schroder,Ronald J. Falk, Susan Sumner. Characterizing the metabolic response of the zebrafish kidney to overfeeding. American Journal of Physiology. 2023;325(4):F491-F502. https://doi.org/10.1152/ajprenal.00113.2023

Evan M. Zeitler EM, J. Charles Jennette, Jennifer E. Flythe, Ronald J. Falk, John S. Poulton. High-calorie diet results in reversible obesity-related glomerulopathy in adult zebrafish regardless of dietary fat. American Journal of Physiology. 2022;322(5):F527-F539. https://doi.org/10.1152/ajprenal.00018.2022