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The UNC Anesthesiology Clinical Trials Research Team specializes in conduct of clinical studies involving medications or devices. Their facilities at the hospital of UNC Health Care and the Adams School of Dentistry allow them to attract a diverse patient population and perform enrollment and study tasks in a regulated clinical research space. This group works with Department of Anesthesiology faculty to manage and conduct both industry-sponsored clinical trials and investigator-initiated studies. Their team of professionals includes three full-time research coordinators as well as regulatory and other support staff. Individual faculty studies performed in collaboration with the clinical trials team are described below.


  • SPR-SPRINT (Grant, PI)Treatment of Post-Operative Pain Following Orthopedic Surgery With SPRINT Peripheral Nerve Stimuation System. 


  • Haisco-USA Pharm (Arora, PI) Efficacy and Safety of HSK3486 Compared to Propofol in Induction of General Anesthesia in Adults Having Elective Surgery
  • POISE-2 (PI, Kumar) – PeriOperative ISchemic Evaluation-2 (POISE-2) Trial 
  • POISE-3 (PI, Kumar)PeriOperative ISchemic Evaluation-3 (POISE-3) Trial 
  • Cleveland Clinic/TAP Study (Rowan, PI) Comparison of Bilateral Transversus Abdominis Plane Block with Exparel versus Continuous Epidural Analgesia with Bupivacaine: A Randomized, Controlled Trial
  • 3M (Coombs, PI) Peripheral Intravenous Catheter Complication Rate Comparison of Two Different Catheter‐ Stabilization Systems (PIV Secural)
  • Cadence (McNaull, PI) A Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of IV Acetaminophen for the Treatment of Acute Pain in Pediatric Patients
  • VistaPharm (Valley, PI)Evaluate The Pharmacokinetics and Safety Of Oxycodone Oral Solution In Pediatric and Adolescent Subjects