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The University of North Carolina at Chapel Hill
Bioinformatics Bldg.
(O) 919-966-4468

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Assistant Professor of Medicine
Dept. of Medicine, Division of Gastroenterology and Hepatology
School of Medicine
University of North Carolina at Chapel Hill

Research Summary

Edward Barnes studies clinical outcomes in patients with Inflammatory Bowel Disease (IBD). He has evaluated clinical outcomes including IBD related surgery among patients using competing strategies of monotherapy or sequentially added combination therapy with anti-TNF therapy and an immunosuppressive agent.  Additionally, he has evaluated the role of diet in flares of Ulcerative Colitis and the correlation between anxiety and depression and IBD specific patient reported outcomes.  More recently, he has used large nationwide databases to evaluate the risk of hospitalization for acute myocardial infarction among patients with IBD and to evaluate risk factors for readmission among patients with established IBD. He has utilized the patient powered research network, IBD Partners to evaluate quality of life among patients with an ileal pouch-anal anastomosis (IPAA) after colectomy. He recently received a grant from the Crohn’s and Colitis Foundation for a prospective pouch-related registry. He is exceptionally trained in Medicine and epidemiology and has outstanding potential that the CGIBD can help nurture.

Relevance of Research to CGIBD Mission: Ed Barnes studies outcomes in patients with inflammatory bowel disease, particularly patients with an ileal pouch anal anastomosis. He collaborates with members of the IBD and Clinical Research Group and benefits from use of the Biostatistics and Clinical Research Core.

CGIBD Focus Area(s):  Clinical/Translational Research

Pilot and Feasibility Award 2017

Collaborators: Barritt, Crockett, Dellon, Egberg, Galanko, Herfarth, Long, Kappelman, Peery, Sandler, Shaheen