Pilot Grants for Gastrointestinal Biology Research
Dates For Next Funding Cycle
Letter of Intent receipt date: March 15, 2021
Application receipt date: April 19, 2021
Oral Presentation: June 8, 2021 (selected applications)
The Center for Gastrointestinal Biology and Disease (CGIBD), a joint program at the University of North Carolina at Chapel Hill and North Carolina State University, awards pilot/feasibility grants each year in a competitive application process. Pilot/feasibility grants are one-year awards of up to $30,000 total costs.
The overall purpose of this program is to provide support for investigators to pursue new and innovative research ideas leading to independent funding. We are particularly interested in projects related to our theme of homeostasis, injury and repair as it relates to digestive and liver diseases. Priority is given to new investigators and investigators who use our core facilities.
A one-page letter of intent should be submitted by the date listed above and must include the following:
- Investigator’s name;
- Investigator’s rank/position;
- Investigator’s department and institutional affiliation;
- Investigator’s mailing address;
- Investigator’s e-mail address;
- Proposed title of the project;
- Brief description of the project
- Investigator’s eligibility criteria based on the following with preference given to those in Category 1 –
- Category 1: new investigators (post-doc or beyond) without current or past NIH research project (R01) support,
- Category 2: established, supported GI investigators who are proposing projects that constitute a significant departure from their ongoing research,
- Category 3: established non-GI investigators who are proposing projects in which they will transfer their special expertise from their fields to the research focus of the Center.
Letters of intent should be submitted to CGIBD P30 Administrator, via e-mail.
The full application package is due on the date listed above. This package must include the cover page, 4 pages of text material (references may be additional pages), line item and narrative budgets, and investigator’s biosketch and other support. Investigators may apply for funding up to a limit of $30,000 in total funds. Please note that there is one form that includes the proposal and budget. All documentation must be submitted as a single PDF. The application form is available at the bottom of this page under Downloads.
The electronic application package is due by 5 PM of the application deadline at this address: PF Application Web page. Applicants are encouraged to call the Administrator at 919.966-8381 with questions about the process. An activated log-in is required for submission.
Funding Mechanism and Regulations
When a research project is funded through the CGIBD Pilot and Feasibility Grant Program, a budget account is established at the CGIBD office for the use of the PI. New awardees should contact the CGIBD P30 Administrator, for precise instructions on how to access the funds. The awards are for 12 months, but awardees may request an automatic no-cost extension.
Awardees will not receive funds until they have provided the CGIBD with documentation of approvals for animal or human subjects use, if either approval is required. In the case of human subjects, the CGIBD will also require assurances that all personnel have been trained in the use of human subjects in research.
In general, funds may be used for any purpose which directly supports the research proposed by the funded application. For example, an awardee may choose to pay some of an assistant’s salary from the funds or may use them to purchase research supplies, order services from any of the campus scientific support cores, or travel to a relevant meeting or workshop. However, funds may not be transferred to another project or to general departmental use. They may not be used to support an advisor or mentor or his/her research. They may not be used to support the general operation of a laboratory, except to the extent that the proposed research uses laboratory resources or to purchase laboratory equipment.
Pilot/feasibility proposals should be based on research in gastrointestinal biology and epidemiology. Preference will be given to proposals that (1) appear likely to result in findings that will allow the investigator to successfully compete for subsequent independent funding and (2) are related to research directions of the UNC Center for Gastrointestinal Biology and Disease. The Center’s primary research theme is homeostasis, injury and repair. Among the areas of special interest are: inflammatory bowel diseases (IBD), liver disease, gastrointestinal cancer, intestinal water and electrolyte transport; gastrointestinal epithelial damage, growth, development and repair; intestinal stem cells; gut microbiome and the epidemiology of gastrointestinal disease. Applications investigating other aspects of gastrointestinal disease will be accepted.
Pilot/feasibility studies may not be used to supplement or extend ongoing funded research or as a general-purpose fund to compensate for errors in budgeting, overspending or unexpected loss of funds on established programs or to contribute to the costs of maintaining a laboratory or core (though funds may be used to pay service or supply fees directly related to the proposed project.) If funds have not been fully expended at the end of the budget period or at the time the applicant receives NIH funding, these may be reclaimed by the CGIBD to support other pilot projects. Questions on the use of funding should be referred to the CGIBD P30 Administrator.
Current P/F recipients may apply for a second year of funding by competitive renewal. Previous P/F recipients may apply for a new award by submitting a new grant proposal that clearly represents a new research direction.
All investigators funded through this program must submit a 6-month progress report and an annual report for inclusion in the CGIBD’s submission to the National Institutes of Health for continuation funds.. Any publications resulting from CGIBD support must credit the CGIBD grant number (P30 DK034987). Awardees should continue to report funding awards and/or publications resulting from their pilot awards as these occur in the future.
All applicants will be notified of the status of their application as soon as possible following review by the CGIBD External Advisory Board. Successful applicants will be asked to meet with the Center biostatistician and administrative staff before receiving funds. The CGIBD P30 Administrator will provide detailed instructions for using funds.
Applications for pilot/feasibility studies will be evaluated initially by the CGIBD Executive Committee. Members of the Executive Committee are Drs. Robert S. Sandler, Nicholas Shaheen, Scott Magness, Tope Keku, Evan Dellon, and R. Balfour Sartor from UNC-CH, Dr. John F. Rawls from Duke, and Drs. Anthony Blikslager, and Susan L. Tonkonogy from NCSU-CVM. Each application will also be reviewed by a scientific content expert. The Executive Committee will rank the applications on the basis of scientific merit, originality of the research initiatives, applicability to Center research directions and the potential to successfully compete for external funds. They will then review the requested budget and make recommendation for approval or disapproval. In general, preference will be given to junior investigators.
The Center’s External Advisory Board, comprised of clinical and basic scientists from outside the universities, will subsequently review approved applications. Members of the External Advisory Board are Kim Barrett, Ph.D., University of California at San Diego; Gail Hecht, MD, University of Illinois at Chicago; Richard Peek, MD, Vanderbilt University; and Gary Wu, MD, University of Pennsylvania. Pilot/feasibility applicants will give brief oral presentations before the committee. The External Advisory Board will decide on funding priority and select which of the approved applications will receive funds.