Research Summary
Dr. Bhatt’s long-term career goal is to use her broad multidisciplinary training to study the complex biochemistry occurring at the host-microbe interface and utilize this knowledge to develop clinical tools to benefit human health. The goal of her research program to identify strategies to mitigate the adverse effects of various medications, thereby expanding and extending their usage and access. The overall objective of her research is to unravel the extent to which bacterial drug metabolism, including that of host-derived drug conjugates, injures the intestinal epithelium, a major site of drug disposition. Elucidating mechanisms of epithelial injury, will also uncover novel strategies to mitigate drug-induced adverse events.
CGIBD Focus Area(s): Microbiome
Pilot and Feasibility Award 2019
Collaborators: Andermann, Fodor, Magness, Redinbo, Sartor