Research Summary
Dr. Garman is a translational scientist, with research that bridges human gastroenterological diseases with bench-science in injury, repair, and carcinogenesis in the gastrointestinal tract. She has focused on basic and translational approaches and developed a large animal (porcine) model of esophageal injury and repair as well as novel 3D culture techniques for esophageal submucosal glands. He lab used these models to investigate mechanisms of repair, metaplasia, and neoplasia in the upper GI tract, and they are collaborating with Case Western on a new P01 focused on esophageal cancer interception. A recent P20 project studied disparities related to H pylori infection, gastric intestinal metaplasia, and gastric cancer. That work has inspired a new research focused on treatment for gastric intestinal metaplasia.
CGIBD Focus Area(s): Regeneration and Repair; Clinical/Translational Research
Pilot Feasibility Award 2013
Collaborators: Blikslager, Gonzalez