Research Summary
Dr. Van Landeghem explores how cues of the microenvironment impact intestinal epithelial (stem) cells in health and cancer, and heavily investigates the role of the enteric nervous system. The body of work generated by her studies has already led to two seminal papers demonstrating for the first time that enteric neurons and glial cells regulate colon carcinogenesis. Her laboratory also currently pursues research projects revolving around how nutritional interventions/imbalances impact enteric glial cell-controlled epithelium functions during development and eating disorders.
CGIBD Focus Area(s): Regeneration and Repair
Pilot and Feasibility Award 2016 & 2018
Collaborators: Blikslager, Gonzalez, Magness, Ziegler