Temitope Keku has a research focus directed at the etiology and prevention of benign, premalignant and malignant gastrointestinal (GI) diseases. She has been involved with projects aimed at understanding the role of genetic susceptibility, gut microbiome, metabolomics and transcriptomics in colon adenomas, CRC and diverticulosis. She has expertise in evaluating molecular biomarkers and genetic factors. She has developed and led multidisciplinary collaborations with scientists locally at UNC and at the national and international levels. She is actively involved as Co-PI on a study evaluating the gut microbiome and other factors in relation to diverticulosis.
Relevance of Research to CGIBD Mission: Tope Keku has conducted research on colorectal adenomas and cancer. She is currently actively involved in translational research on diverticulosis and microscopic colitis. During the current funding cycle for the CGIBD she has directed the Histology Core. We have proposed to sunset the Histology Core as part of the CGIBD, although we will continue to offer histology service as a UNC Recharge Center. Dr. Keku will serve as an Assistant Director of the CGBID and Director of Enrichment and Diversity Initiatives if this application is funded.
CGIBD Focus Area(s): Microbiome, Clinical/Translational Research
Pilot and Feasibility Award 1999
Collaborators: Azcarate, Fodor, Galanko, Peery, Sandler, Yeh