James S. Hagood, MD

Director, Program for Rare and Interstitial Lung Disease Professor, Pediatric Pulmonology

Dr. Hagood is a pediatric pulmonologist specializing in rare lung disease. His “Lung Repair Lab” studies the molecular regulation of fibroblast phenotypes in pulmonary fibrotic disease and lung alveolarization. He also studies the roles and regulation of Thy-1, a critical modulator of cellular phenotype, and epigenetic/epigenomic alterations in lung development and disease, as well as targeted therapy for diffuse lung diseases.

Additionally, the lab studies the role of extracellular vesicles, such as exosomes, in altering cell phenotypes in the context of lung repair and remodeling. Dr. Hagood has been part of the launch of large collaborative efforts to create comprehensive cellular and molecular maps of the lung: the LungMAP, funded by the National Heart, Lung and Blood Institute (NHLBI), and more recently the HuBMAP, supported by the NIH Common fund, and the Normal Aging Lung Cell Atlas, funded by the NHLBI.

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To learn more about how you can support the Children’s Research Institute, contact Keela Lyon, Senior Executive Director of Development, UNC Medicine, Children’s. Email or phone 919-843-2915.
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