Lecture Series
The Children’s Research Institute Lecture Series encourages interaction between researchers investigating childhood diseases, and stimulates new research through exposure to cutting-edge, ongoing work.
“Organotypic co-culture models to investigate the pro-fibrotic effects of airborne toxicants”
December 10, 2024
12:00-1:00 pm
Mary Ellen Jones 3116 or Zoom
Elizabeth Corteselli is an Assistant Professor in the Department of Pediatrics working in the Center for Environmental Medicine, Asthma, and Lung Biology. Her laboratory is interested in the mechanisms by which environmental exposures induce airway epithelial cell injury and contribute to the pathogenesis of fibrotic lung disease. Her lab uses a combination of in vivo studies, human samples, and advanced in vitro models to investigate this topic.
Please contact childrensresearch@med.unc.edu for Zoom details.
“Single-Cell RNA sequencing reveals Chlamydia trachomatis-driven T cell activation and differentiation in cervical mucosal immunity”
January 14, 2025
12:00-1:00 pm
Mary Ellen Jones 3116 or Zoom
Dr. Zheng is a multidisciplinary scientist specializing in systems immunology of infectious diseases and vaccines, human genetics, and biostatistics. Currently a Professor in the Department of Pediatrics at the University of North Carolina at Chapel Hill, she has extensive experience working with large infectious disease cohorts and conducting multi-omics data analyses. Her primary interest lies in identifying protective systemic blood and local mucosal cellular immune responses as well as antibody responses against bacterial or viral infections and diseases. To address the challenges of multi-level omics and multi-cohort data analysis, her team has developed a series of new statistical methods for causal network analysis, causal mediation analysis, digital immune cell separation, rigorous multi-study normalization and batch effect correction, and integrative single cell sequencing (scRNA-seq) and bulk RNA-seq data analysis.
Please contact childrensresearch@med.unc.edu for Zoom details.