Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life
Authors
Vielot NA, Brinkman A, DeMaso C, Vilchez S, Lindesmith LC, Bucardo F, Reyes Y, Baric RS, Ryan EP, Braun R, Becker-Dreps S.
Abstract
We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months of age. Antibody increases after 3 months suggested natural infections. This information could guide the timing of future norovirus vaccines.
Citation
Vielot NA, Brinkman A, DeMaso C, Vilchez S, Lindesmith LC, Bucardo F, Reyes Y, Baric RS, Ryan EP, Braun R, Becker-Dreps S. Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life. J Pediatric Infect Dis Soc. 2022 Oct 25;11(10):463-466. doi: 10.1093/jpids/piac067. PMID: 35849145.
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