Author Archives: btuftin

Four lab members presented some of our ongoing research as posters at the ASHG annual meeting in Boston in mid-October. Emily Drzymalla presented Alzheimer’s Disease PRS, APOE, and Family History in in All of Us Madeline Gillman presented Assessment of protein slope QTLs in the Multi-Ethnic Study for Atherosclerosis (MESA)...

With colleagues, Raffield lab graduate student Micah Hysong recently published a paper in Blood Advances “Characterization of the phenotypic consequences of the Duffy-null genotype.”

Raffield lab had a strong presence at ASHG 2024 in Denver presenting ongoing research.

Laura Raffield has received a U01 grant from NIA for a proposal to investigate the higher risk of Alzheimer’s disease and related dementias (ADRD) for Black adults compared with non-Hispanic White adults. The project “hypothesize[s] that inflammation may be a key feature linking cardiometabolic and social determinants of health disparities...

Madeline Gillman, Daeeun Kim and Jayna Nicholas received travel awards to the May 22-24 CHARGE meeting in Denver where Madeline presented on Influence of Longitudinal Proteomic Trajectories on Cardiac Structure and Function in the Atherosclerosis Risk in Communities (ARIC) Study, Daeeun presented on The Impact of Long-term Exposure to Air Pollution...

Micah Hysong received a NSF Graduate Research Fellowship, a five-year fellowship that provides three years of financial support. The goal of the NSFGR Program is to “broaden participation of the full spectrum of diverse talents in STEM.” Micah was selected based on his his research proposal “Leveraging Multi-omic data from...

Researchers from the Raffield lab, as well as Raffield lab collaborators from the Li lab group had presentations or posters at the American Society for Human Genetics annual meeting (Nov. 1-5 2023). Brian Chen held his oral presentation Proteome-Wide Association Study Using Cis and Trans Variants and Applied to Blood...

Katherine was awarded the Biostatistics Undergraduate Summer Internships (BUSI) Program End-of-Summer Research Symposium Best Poster Award for her poster Cross-Platform Comparison of Type 2 Diabetes Proteomic Signatures in the Jackson Heart Study. This award is given annually to most accomplished poster presentations at the symposium.

Madeline Gillman was appointed to the Bioinformatics and Computational Biology (BCB) T32 Training Grant. Her proposal focused on QTLs for longitudinal ‘omic trajectory measures in TOPMed. Congratulations, Madeline!

CCA is a correlation-based method for multi-omics data which reduces the dimension of each omic assay to several orthogonal components–commonly referred to as canonical variables (CVs). The widely-used SMCCA method allows effective dimension reduction and integration of multi-omics data, but suffers from potentially highly correlated CVs when applied to high-dimensional...