Author Archives: btuftin

Emily Drzymalla presented the poster “Association between neutrophil to lymphocyte ratio and Alzheimer’s disease (AD) in large biobank cohorts” at the Alzheimer’s Association International Conference (AAIC) meeting in Amsterdam July 19, 2023. We look forward to sharing a manuscript describing these findings soon!

Le Huang presented the poster “Metabolite prediction models in UK Biobank: A metabolome-wide association study (MWAS)“ at the American Society of Human Genetics (ASHG) meeting in Los Angeles, Oct, 2022. We look forward to sharing a manuscript describing these findings soon.

With many collaborators from TOPMed, the Raffield lab was pleased to contribute to recent whole genome sequencing based publications for red blood cell, white blood cell, and platelet related traits. These publications identified novel single variant signals for these heritable hematological measures, despite the 10x smaller sample size versus existing...

Jayna Nicholas was appointed to the Genetics and Molecular Biology (GMB) T32 Training Grant. Her proposal focused on improved understanding of discordant pQTLs across proteomics platforms in diverse cohort studies from TOPMed. Congratulations, Jayna!

Platelets play a key role in thrombosis and hemostasis. Platelet count (PLT) and mean platelet volume (MPV) are highly heritable quantitative traits, with hundreds of genetic signals previously identified, mostly in European ancestry populations. We here utilize whole genome sequencing (WGS) from NHLBI's Trans-Omics for Precision Medicine initiative (TOPMed) in...

Sarthi Patil was awarded the Biostatistics Undergraduate Summer Internships (BUSI) Program End-of-Summer Research Symposium Best Poster Presentation Award for her poster entitled TWAS Training for Jackson Heart Study Cohort. Sarthi is working to train transcriptome-wide association study (TWAS) models using newly generated RNA-seq data from the Jackson Heart Study. Congratulations,...

Jayna Nicholas presented the poster “Fibrinogen Associated Plasma Metabolites and Implications for Cardiovascular Disease Risk“ at the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) meeting in Philadelphia, PA April 28, 2022. We look forward to sharing a manuscript describing these findings soon.