About

• Mentorship Training Completions:
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• Department Affiliations:
• Biochemistry and Biophysics; Pharmacology; Cell Biology and Physiology

• Other UNC PhD Program Affiliations:
• Biochemistry and Biophysics; Pharmacology; Cell Biology and Physiology

My Research

Our lab studies the regulation of the mammalian cell division cycle with a particular focus on the cell cycle phase transitions related to DNA replication and to cell cycle exit. We wonder how cells manage to ensure that replication doesn‚Äôt occur under inappropriate circumstances, and how cell proliferation is controlled during development and maintenance of an adult organism. It’s becoming increasingly clear that cancer cells initiate DNA replication inappropriately and furthermore, that they do a “sloppy” job of precisely duplicating and segregating their genomes. We seek to determine how the cell cycle is normally controlled and how that control is altered during normal developmental transitions or is disrupted in disease.