Areas of Interest
My research focuses on elucidating genetic mechanisms underlying stemness and developing translational models to establish a finer understanding of stem cell-driven regeneration dynamics in homeostasis and injury. Using a combination of genetic mouse models and micro-fabricated bioengineered platforms, we are exploiting the self-renewal capacity and multipotency of ISCs to develop long-term ex vivo models of the intestine and colon with primary tissues. These biomimetic models offer new solutions for compound screening and cell-based therapies.
Education and Training
- Undergraduate University of California, San Diego
- PhD University of North Carolina at Chapel Hill
- Post-Doctoral Research UNC GI Division, Molecular Pathogenesis of Liver Fibrosis
- Post-Doctoral Research UNC Department of Genetics, Neural Stem Cells