Scott T. Magness, PhD
Associate Professor of Medicine, Cell Biology, and Biomedical Engineering
Areas of Interest
My research focuses on elucidating genetic mechanisms underlying stemness and developing translational models to establish a finer understanding of stem cell-driven regeneration dynamics in homeostasis and injury. Using a combination of genetic mouse models and micro-fabricated bioengineered platforms, we are exploiting the self-renewal capacity and multipotency of ISCs to develop long-term ex vivo models of the intestine and colon with primary tissues. These biomimetic models offer new solutions for compound screening and cell-based therapies.
University of California, San Diego
University of North Carolina at Chapel Hill
UNC GI Division, Molecular Pathogenesis of Liver Fibrosis
UNC Department of Genetics, Neural Stem Cells