About

Dr. Olivier’s main clinical and research focus is on bronchiectasis and chronic airway infections, particularly those caused by the environmental nontuberculous mycobacteria (NTM). His research interests include the population distribution and characteristics of disease, host susceptibility and pathogenesis, and management optimization for chronic pulmonary NTM infections. Dr Olivier’s work on host pathogenesis has identified overlap between idiopathic bronchiectasis patients with NTM infections and gene variants associated with genetic disorders of mucociliary clearance (cystic fibrosis and primary ciliary dyskinesia), heritable connective tissue disorders (e.g. Marfan, Ehlers-Danlos syndromes) and primary immune deficiencies. He is an investigator in the NIH-funded Genetic Disorders of Mucociliary Clearance Consortium with a focus on primary ciliary dyskinesia and other causes of suppurative respiratory tract disease. Therapeutic development interests include both a bench focus on Mycobacterium abscessus preclinical model development, virulence and therapeutic targets and clinical trial optimization for novel antimicrobial therapeutics.