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Michael Knowles, MD - Division of Pulmonary Diseases and Critical Care Medicine

Michael Knowles, MD

Professor of Medicine

Contact Information

Address

Office :
7215 Marsico Hall
,

Resources

Michael Knowles, MD

Professor of Medicine

Areas of Interest

Genetic disorders of mucociliary clearance, including gene modifiers of disease phenotype in cystic fibrosis (CF) lung and liver disease, primary ciliary dyskinesia (PCD), as well as idiopathic bronchiectasis.

About

Research Focus: Dr. Michael R. Knowles is a Professor of Pulmonary and Critical Care Medicine at UNC. He has over 3 decades of clinical research experience that spans across the disciplines of biology, physiology, genetics and clinical trials in both the academic and private sectors. He is currently the head of two large multicenter studies: 1) Genetic Modifiers of Disease phenotype (severity) in cystic fibrosis lung and liver disease, which includes an International Consortium doing whole genome and differential gene expression studies; and 2) a Consortium with 8 sites in North America to study rare genetic disorders of mucociliary clearance, and non-CF/non-PCD (idiopathic) bronchiectasis.

 

 

  • BA

    University of North Carolina at Chapel Hill

  • MD

    University of North Carolina at Chapel Hill

  • Residency

    Ohio State University

  • Fellowship

    University of North Carolina at Chapel Hill