Division Chief, Pediatric Endocrinology
Associate Professor
Departments of Pediatrics and Nutrition
Research
Nutritional Immunology and Immunometabolism
Publications
- Green WD, Alwarawrah Y, Al-Shaer AE, Shi Q, Armstrong M, Manke J, Reisdorph N, Farrell TM, Hursting SD, MacIver NJ, Beck MA, Shaikh SR. Inflammation and Metabolism of Influenza-Stimulated Peripheral Blood Mononuclear Cells From Adults With Obesity Following Bariatric Surgery. J Infect Dis. 2022 Dec 28;227(1):92-102. doi: 10.1093/infdis/jiac345. PubMed PMID: 35975968; PubMed Central PMCID: PMC10205606.
- Shaw BI, Lee HJ, Ettenger R, Grimm P, Reed EF, Sarwal M, Stempora L, Warshaw B, Zhao C, Martinez OM, MacIver NJ, Kirk AD, Chambers ET. Malnutrition and immune cell subsets in children undergoing kidney transplantation. Pediatr Transplant. 2022 Dec;26(8):e14371. doi: 10.1111/petr.14371. Epub 2022 Aug 8. PubMed PMID: 35938682; PubMed Central PMCID: PMC9669171.
- Greene E, MacIver NJ. Targeting T cell (oxidative) metabolism to improve immunity to viral infection in the context of obesity. Front Immunol. 2022;13:1025495. doi: 10.3389/fimmu.2022.1025495. eCollection 2022. Review. PubMed PMID: 36275776; PubMed Central PMCID: PMC9583400.
- Shaikh SR, MacIver NJ, Beck MA. Obesity Dysregulates the Immune Response to Influenza Infection and Vaccination Through Metabolic and Inflammatory Mechanisms. Annu Rev Nutr. 2022 Aug 22;42:67-89. doi: 10.1146/annurev-nutr-062320-115937. Review. PubMed PMID: 35995048; NIHMSID:NIHMS1892696.
- Andonian BJ, Koss A, Koves TR, Hauser ER, Hubal MJ, Pober DM, Lord JM, MacIver NJ, St Clair EW, Muoio DM, Kraus WE, Bartlett DB, Huffman KM. Rheumatoid arthritis T cell and muscle oxidative metabolism associate with exercise-induced changes in cardiorespiratory fitness. Sci Rep. 2022 May 6;12(1):7450. doi: 10.1038/s41598-022-11458-4. PubMed PMID: 35523821; PubMed Central PMCID: PMC9076829.
- Huang Y, Zou Y, Jiao Y, Shi P, Nie X, Huang W, Xiong C, Choi M, Huang C, Macintyre AN, Nichols A, Li F, Li CY, MacIver NJ, Cardona DM, Brennan TV, Li Z, Chao NJ, Rathmell JC, Chen BJ. Targeting Glycolysis in Alloreactive T Cells to Prevent Acute Graft-Versus-Host Disease While Preserving Graft-Versus-Leukemia Effect. Front Immunol. 2022;13:751296. doi: 10.3389/fimmu.2022.751296. eCollection 2022. PubMed PMID: 35296079; PubMed Central PMCID: PMC8920494.
- Alwarawrah Y, Danzaki K, Nichols AG, Fee BE, Bock C, Kucera G, Hale LP, Taylor GA, MacIver NJ. Irgm1 regulates metabolism and function in T cell subsets. Sci Rep. 2022 Jan 17;12(1):850. doi: 10.1038/s41598-021-04442-x. PubMed PMID: 35039539; PubMed Central PMCID: PMC8763923.
- Green WD, Al-Shaer AE, Shi Q, Gowdy KM, MacIver NJ, Milner JJ, Beck MA, Shaikh SR. Metabolic and functional impairment of CD8(+) T cells from the lungs of influenza-infected obese mice. J Leukoc Biol. 2022 Jan;111(1):147-159. doi: 10.1002/JLB.4A0120-075RR. Epub 2021 Apr 13. PubMed PMID: 33847405; PubMed Central PMCID: PMC8787296.
- Dudzinski SO, Bader JE, Beckermann KE, Young KL, Hongo R, Madden MZ, Abraham A, Reinfeld BI, Ye X, MacIver NJ, Giorgio TD, Rathmell JC. Leptin Augments Antitumor Immunity in Obesity by Repolarizing Tumor-Associated Macrophages. J Immunol. 2021 Dec 15;207(12):3122-3130. doi: 10.4049/jimmunol.2001152. Epub 2021 Nov 12. PubMed PMID: 34772698; PubMed Central PMCID: PMC9095767.
- David E, Zhu M, Bennett BC, Cheng D, Schroder P, Nichols A, Parker W, Kirk AD, MacIver N, Chambers ET. Undernutrition and Hypoleptinemia Modulate Alloimmunity and CMV-specific Viral Immunity in Transplantation. Transplantation. 2021 Dec 1;105(12):2554-2563. doi: 10.1097/TP.0000000000003743. PubMed PMID: 33724247; PubMed Central PMCID: PMC9588407.
