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7/6/09: Zylka lab shows that a G protein-coupled receptor enhances excitability in pain-sensing neurons

July 6, 2009
In an article published in J. Neuroscience, Mark Zylka’s lab, in collaboration with labs at Caltech and the University of Pittsburgh, found that Mrgprd enhancesexcitability in nociceptive neurons. In addition, they found that Mrgprd molecularly marks a population of unmyelinated polymodal nociceptors. Polymodal nociceptors were first physiologically identified and studied...

Philpot lab reverses plasticity defects in a mouse model of the mental retardation Angelman syndrome

May 26, 2009
  In a paper published in this week’s issue of Nature Neuroscience researchers in Ben Philpot’s lab have discovered in mice how a single disrupted gene can cause a form of severe mental retardation known as Angelman syndrome, an autism spectrum disorder. In a study published in the journal Nature...

5/08/09: 9th Annual Perl/UNC Neuroscience Prize awarded to Michael Greenberg, PhD

May 8, 2009
The 9th Annual Perl/UNC Neuroscience Prize was awarded to Dr. Michael Greenberg from Harvard Medical School this past Wednesday, May 6th. Dean Roper presented Dr. Greenberg with the plaque and check. The title of Dr. Greenberg’s lecture was “Signaling Networks that Regulate Synapse Development and Cognitive Function.” More than 200...

1/26/09:Anton and Snider labs show that the tumor supressor gene (APC) is crucial for brain development

January 26, 2009
In this paper published in the January 15th issue of Neuron, the Anton and Snider labs found that APC, a protein normally thought of as important for certain types of intestinal cancers, is critical for the formation of cerebral cortex. APC is essential to the development and maintenance of the...

12/16/08: Deshmukh lab identifies novel mechanism used by neurons to evade cell death

December 16, 2008
In a paper published in Nature Cell Biology, Allyson Vaughn and Mohanish Deshmukh have identified a strikingly similar mechanisms used by neurons and cancer cells to evade cell death. Neurons and cancer cells are very different by most criteria, yet have the common characteristic of extensively utilizing glucose. Here, we...

12/03/08: Core Facility upgrades

December 3, 2008
UNC Neuroscience Center is pleased to announce that the Confocal and Multiphoton Imaging Core has received a major upgrade with the installation of a new Olympus Confocal microscope. The Olympus FV1000 confocal microscope is specifically designed for long-term imaging of living neuronal tissue. It is equipped with a dedicated environmental...

Zylka lab publishes cover article in Neuron

October 23, 2008
Congratulations to Mark Zylka, Nate Sowa and Bonnie-Taylor Blake for publishing the cover article in the October 9 issue of Neuron (www.neuron.org). In their paper, they found the transmembrane isoform of Prostatic Acid Phosphatase (PAP) plays a critical role in pain mechanisms. PAP is expressed in pain-sensing neurons, encodes the...

10/23/08: Helen Lyng White Fellowship

October 23, 2008
We are pleased to announce that Holden Higginbotham has been selected as this year’s Helen Lyng White Fellow in Neuroscience Research. Holden did his PhD work with Dr. Joseph Gleeson at the University of California San Diego, where he published studies on neuron migration in developing cerebral cortex. At UNC,...

10/20/2008: More than 225 neuroscientists attend 9th Annual UNC Neuroscience Symposium

October 20, 2008
The 9th Annual UNC Neuroscience Symposium was held Thursday, Oct 16th at the Carolina Club with more than 225 neuroscientists from UNC and other Triangle institutions in attendance. Catherine Dulac, PhD, Sebastian Seung, PhD, Marc Raichle, MD, and Arturo Alvarez-Buylla, PhD were the speakers at this year’s event.

9th Annual UNC Neuroscience Symposium- Speaker times and titles

October 1, 2008
We are pleased to announce the 9th Annual UNC Neuroscience Symposium will be held on Thursday, October 16, 2008 from 9am until 1pm. The event will again be held at the Carolina Club on UNC Campus. We invite you all to attend! 9th Annual UNC Neuroscience Symposium 9:00am – 9:50am...