News
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Advancing Brain Research: The Frohlich Lab’s Work in Neurostimulation and Mental Health
The Frohlich Lab, led by Flavio Frohlich, PhD, professor of psychiatry and of the Carolina Center for Neurostimulation, and specializes in groundbreaking research and developing innovative approaches to combating mental health issues. Watch a video about this research here.
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UNC Neuroscience Faculty Receive BBRF Distinguished Investigator Grants
In 2025, the Brain & Behavior Research Foundation awarded Distinguished Investigator Grants valued at $1 million to 10 senior-level scientists who are conducting groundbreaking research in neurobiological and behavioral science. Recipients of the $100,000, one-year grants are exploring critical areas of mental health, including opioid use disorder, depression in pregnant women, schizophrenia, bipolar disorder, and the effects … Read more
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FDA Grants Breakthrough Device Designation for Non-Invasive Brain Stimulation Device to Treat Major Depressive Disorder
With a designation from the FDA, a device created and patented by Flavio Frohlich, PhD, professor of psychiatry at the UNC School of Medicine and member of the UNC Neuroscience Center, is one step closer to being available for patients. Original full article can be found here.
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Eight Psychiatric Disorders Share the Same Genetic Causes, Study Says
A new genetic study, led by Hyejung Won, PhD, associate professor in the Department of Genetics and the UNC Neuroscience Center, and Patrick Sullivan, MD, FRANZCP, the Yeargen Distinguished Professor of Psychiatry and Genetics, has successfully delineated the functional consequences of genetic variants into two groups. Their findings, which were published in Cell, suggest that pleiotropic variants may be optimal targets for treatment, … Read more
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Structure-guided design of a peripherally restricted chemogenetic system
Kang et al. present HCAD, a peripherally restricted DREADD based on HCA2, with a chemical actuator that avoids crossing the blood-brain barrier and selectively reduces pain in mice. This system will enable the study of peripheral physiology without affecting the central nervous system. Publication found here.