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  • NIH Award Leads to Deeper Study of Brain Malformations

    How seizures, epilepsy and other brain malformations develop from genetic variants is not fully understood, but a new National Institutes of Health (NIH) award will pave the way toward understanding the cause and potentially lead to new therapies. Original article can be found here.

  • Researchers Identify Potential Treatment for Angelman Syndrome

    Researchers in the lab of Ben Philpot, PhD, the Kenan Distinguished Professor of Cell Biology and Physiology at the UNC School of Medicine and associate director of the UNC Neuroscience Center, have identified a small molecule that could lead to a safe and effective treatment for the neurodevelopmental condition known as Angelman syndrome. Original article … Read more

  • Researchers Wrestle with Accuracy of AI Technology Used to Create New Drug Candidates

    The UNC School of Medicine lab of Bryan Roth, MD, PhD, and colleagues at UCSF, Stanford and Harvard determined that a protein prediction technology can yield accurate results in the hunt to efficiently find the best possible drug candidates for many conditions. Original article can be found here.

  • Scientists Discover Surprising Details about Xylazine in Combination with Fentanyl

    The UNC School of Medicine lab of Zoe McElligott, PhD, and colleagues found that the animal tranquilizer xylazine activates opioid receptors in the brain, suggesting a reason why the treatment naloxone triggers a more severe withdrawal response when given to individuals on fentanyl/xylazine and suffering from respiratory depression. Original article can be found here.

  • Researchers Discover How We Perceive Bitter Taste

    A new study in the lab of Bryan Roth, MD, PhD, at the UNC School of Medicine, helps us better understand how we perceive bitter taste on a chemical level. The findings may lead to the development of drugs that targeting taste receptors. Full article can be found here.