Bryan Roth, PhD, and his lab report the first crystal structure of LSD bound to one of its molecular targets, the serotonin 5-HT2B receptor.
In Volume 168, Issue 3 of Cell, Bryan Roth, PhD, and his lab report the first crystal structure of LSD bound to one of its molecular targets, the serotonin 5-HT2B receptor. This structure reveals the basis for LSD’s long-lasting effects and suggests ways to selectively alter receptor signaling. Read the article here.
Roth also gave an audio interview on the article, which can be listened to here.