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Social Buffering of Posttraumatic Stress Disorder: Longitudinal Effects and Neural Mediators

May 8, 2025
In the context of post-traumatic stress disorder (PTSD), there are few studies which explore how social support mitigates stress symptoms within the acute post-trauma time frame. Our study aims to explore the neural basis of social buffering in trauma recovery. Importantly, social support is a low cost and low risk...

Sex Differences in Response Inhibition-Related Neural Predictors of Posttraumatic Stress Disorder in Civilians With Recent Trauma

May 8, 2025
This study explores sex differences in neural activation during response inhibition and how these differences relate to the development and progression of posttraumatic stress disorder (PTSD) after recent trauma. It found that females with lower activation in the ventromedial prefrontal cortex during inhibition were more likely to develop severe PTSD...

Making Correctional Health Care Education Integral to Health Care Training

May 8, 2025
Health care for incarcerated individuals remains an underserved area with poor health outcomes compared to the general public. The authors summarize the history of structural inequities within the correctional system; discuss the impact of incarceration on individual, family, and community health; and suggest methods to expand didactic curricula and direct...

The developing visual system: a building block on the path to autism

April 4, 2025
This article reviews what is known about the developing visual system in ASD in the first years of life; it also explores the potential canalizing role that atypical visual system maturation may have in the emergence of ASD by placing findings in the context of developmental cascades involving brain development,...

Individual differences in punished alcohol self-administration are unaltered by alcohol vapor exposure

April 4, 2025
Alcohol drinking that persists despite negative consequences is a core feature of alcohol use disorder (AUD). Here we investigate whether individual variability in this behavior are due to extended alcohol exposure or pre-existing differences in rats.

Loss of excitatory inputs and decreased tonic and evoked activity of locus coeruleus neurons in aged P301S mice

April 4, 2025
In this manuscript we used a mouse model of dementia that harbors a human mutation in the tau protein. We found that neurons that are lost in Alzheimer’s Disease (locus coeruleus norepinephrine neurons) have reduced function as compared to their age matched controls.

Explainable artificial intelligence to quantify adenoid hypertrophy-related upper airway obstruction using 3D Shape Analysis

April 4, 2025
We developed an explainable AI model that analyzes 3D CBCT scans to automatically classify and measure upper airway obstruction caused by adenoid hypertrophy in children. This tool provides clinicians with clear visual explanations and accurate assessments to support diagnosis and treatment planning.

Factors Associated with Leaving Ambulatory Psychiatric Treatment in a Large, Academic Health System During the COVID-19 Pandemic

April 4, 2025
Factors identified with a higher odds of leaving outpatient psychiatric care during COVID-19 included demographic (male sex, uninsured (self-pay) status), behavioral (inactive patient health portal), and diagnostic (anxiety and trauma stressor disorders, pervasive and specific developmental disorders, and disorders of childhood) factors. These results highlight that the reasons patients left...

Zuranolone for Postpartum Depression After Highly Lethal Suicide Attempt: Two Case Illustrations and a Narrative Literature Review

April 4, 2025
Our women’s mood disorders group produced this case series on our experience treating patients with zuranolone for severe postpartum depression with suicidality.

The effects of estradiol on subcortical brain volumes in perimenopausal-onset depression

April 4, 2025
Estrogen treatment during menopause increased right hippocampal volumes in women without depression.