Category: Research Publications

Connectivity between the networks in the brain responsible for processing visual input and coordinating response to stimuli may play an important role in social affect symptom variability among children with ASD and those with genetic liability for ASD. These findings align with and extend earlier reports in this sample of...

Connection Learning Healthcare System, one of the eight hubs of the National Institute of Mental Health funded Early Psychosis Intervention Network, supports uniform data collection, analysis, feedback and infrastructure development to promote a culture of continuous quality improvement across 25 Coordinated Specialty Care programs serving young people experiencing first episode...

Fluctuations in sex hormones may impact risk for PTSD, as estradiol has been shown to influence PTSD severity and biomarkers of PTSD. Using the AURORA data, we were able to examine how estradiol levels at the time of the trauma were associated with changes in autonomic function and fear learning...

Post-traumatic stress (PTS) symptoms and substance use behaviors commonly co-occur after a traumatic event. However, whether individual-, household-, or neigborhood-level factors impact this relationship is understudied due to lack of data on long-term outcomes and geographic variability in samples. From the Advancing Understanding of RecOvery afteR traumA (AURORA) study, we...

In the context of post-traumatic stress disorder (PTSD), there are few studies which explore how social support mitigates stress symptoms within the acute post-trauma time frame. Our study aims to explore the neural basis of social buffering in trauma recovery. Importantly, social support is a low cost and low risk...

This study explores sex differences in neural activation during response inhibition and how these differences relate to the development and progression of posttraumatic stress disorder (PTSD) after recent trauma. It found that females with lower activation in the ventromedial prefrontal cortex during inhibition were more likely to develop severe PTSD...

Health care for incarcerated individuals remains an underserved area with poor health outcomes compared to the general public. The authors summarize the history of structural inequities within the correctional system; discuss the impact of incarceration on individual, family, and community health; and suggest methods to expand didactic curricula and direct...

This article reviews what is known about the developing visual system in ASD in the first years of life; it also explores the potential canalizing role that atypical visual system maturation may have in the emergence of ASD by placing findings in the context of developmental cascades involving brain development,...

Alcohol drinking that persists despite negative consequences is a core feature of alcohol use disorder (AUD). Here we investigate whether individual variability in this behavior are due to extended alcohol exposure or pre-existing differences in rats.

In this manuscript we used a mouse model of dementia that harbors a human mutation in the tau protein. We found that neurons that are lost in Alzheimer’s Disease (locus coeruleus norepinephrine neurons) have reduced function as compared to their age matched controls.