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Biobehavioral mechanisms underlying testosterone and mood relationships in peripubertal female adolescents

October 5, 2023
Peripubertal female adolescents who are mood sensitive to changes in testosterone (i.e., experience increased mood symptoms with changes in testosterone) show disturbances in frontal brain activity important for cognitive control and blunted physiological responses to a psychosocial stress test.

Impaired mnemonic discrimination in children and adolescents at risk for schizophrenia

July 10, 2023
People with schizophrenia and their high-risk, first-degree relatives report widespread episodic memory impairments that are purportedly due, at least in part, to failures of mnemonic discrimination. Here, we examined the status of mnemonic discrimination in 36 children and adolescents (aged 11-17 years) with and without familial risk for schizophrenia by...

Aperiodic Neural Activity is a Better Predictor of Schizophrenia than Neural Oscillations

July 10, 2023
Diagnosis and symptom severity in schizophrenia are associated with irregularities across neural oscillatory frequency bands, including theta, alpha, beta, and gamma. However, electroencephalographic signals consist of both periodic and aperiodic activity characterized by the (1/fX) shape in the power spectrum. In this paper, we investigated oscillatory and aperiodic activity differences...

Associations of alcohol and cannabis use with change in posttraumatic stress disorder and depression symptoms over time in recently trauma-exposed individuals

July 10, 2023
In this study involving recent trauma-exposed civilians, researchers aimed to understand the complex relationship between substance use, posttraumatic stress disorder (PTSD), and depression. They utilized a large multisite dataset and tracked alcohol and cannabis use trajectories as well as PTSD and depression symptoms over a span of 3 months. The...

Anxiety Screening: Evidence Report and Systematic Review for the US Preventive Services Task Force.

July 10, 2023
Evidence was insufficient to draw conclusions about the benefits or harms of anxiety screening programs. However, clear evidence exists that treatment for anxiety is beneficial, and more limited evidence indicates that some anxiety screening instruments have acceptable accuracy to detect generalized anxiety disorder.

Depression and Suicide Risk Screening: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.

July 10, 2023

Aperiodic Neural Activity is a Better Predictor of Schizophrenia than Neural Oscillations

July 10, 2023
EEG signals consist of both periodic and aperiodic activity, characterized by the (1/fX) shape in the power spectrum but the utility of this activity has not been examined in a task between schizophrenia patients and healthy control participants. We discovered that the steepness of the power spectrum better-predicted group status...

Striatal dopamine in anhedonia: A simultaneous [11C]raclopride positron emission tomography and functional magnetic resonance imaging investigation

July 10, 2023
This study used to simultaneous PET-MR to detect reduced striatal dopamine functioning during reward processing and blunted mesocorticolimbic network functional connectivity in a transdiagnostic sample with clinically significant anhedonia.  

Handbook of Self-Compassion

June 6, 2023
This handbook examines contemporary issues in self-compassion science and practice. It describes advances in the conceptualization and measurement of self-compassion as well as current evidence from cross-sectional and experimental research. The volume addresses the foundational issues of self-compassion, including its relationship to self-esteem and mindfulness. In addition, it considers the...

Day-to-day individual alpha frequency variability measured by a mobile EEG device relates to anxiety

June 6, 2023
Investigators used an at-home EEG recording device to monitor the changes in individual alpha frequency (IAF), a unique brain activity signature in the 8-12 Hz frequency band. IAF day-to-day variability was found to be stable over a 1 month period and was also found to be related to trait anxiety.