Category: Research Publications

Fifty-nine adolescents (Mage = 15.81, 70% female) with subsyndromal depressive symptomswere randomized to group-based Mindful Self-Compassion for Teens (N = 30) or a newly developed active control Healthy Lifestyles group (N = 29). Results indicated that the risk of developing clinically significant depression was 2.6 times higher in the control...

Among 272 older breast cancer survivors, 15% experienced high depressive symptom trajectories over a 3-year period after diagnosis. Baseline anxiety, frailty, and lower social support were associated with worse outcomes.

We investigate the development of cortical structure-function coupling in children longitudinally scanned at 1, 2, 4, and 6 years old. We found that regional patterns of structure-function coupling in early childhood that were consistent with adult patterns.

In the largest analysis of postpartum depression (PPD) genetics, we have provided estimates of the genetic contribution to this debilitating disorder. Also, we have shown that PPD has similar genetics to other psychiatric traits. Lastly, PPD associated genetic regions may affect neurons also targeted recently approved therapeutics specifically for PPD...

Two-hit models of neurodevelopmental disorders have the power to reveal underlying vulnerability that may not be detected in studies employing only genetic or environmental alterations. In this review, we summarize existing literature that investigates detrimental interactions between prenatal stress and genes associated with neurodevelopmental disorders, with a focus on behavioral...

Investigation of the extent to which rashes associated with Bartonella infection are associated with symptoms of depression, anxiety and schizotypy.

Transgender and gender diverse (TGD) individuals face higher rates of stressors driving disproportionate health risks. Although psychiatric conditions are important to consider in the context of greater health-promoting efforts for TGD youth, any mental health concerns may or may not be related to gender identity or associated dysphoria. Nevertheless, it...

Persistent chronic stress can influence how the brain reacts to traumatic and stressful events; however, it was unclear how neighborhood-level stress impacts brain structure and function. Using AURORA neuroimaging data, we found neighborhood socioeconomic disadvantage, derived from U.S. Census data, had specific associations with threat-related neurobiology which varied with different...

Using rsfMRI data from over 100k individuals across private and public datasets, we identified replicable unique patterns of brain connectivity.

This paper presents a novel method for detecting ovulation in peripubertal adolescents and provides an openly accessible R-script to determine ovulatory status based on hormone profiles (estrogen, progesterone and LH) across the menstrual cycle.