Category: Research Publications

As our country aims to implement measures to decrease suicide, of which over half are due to firearms, we explore the role of ERPO (Extreme Risk Protection Order) laws to temporarily remove guns from individuals at elevated risk.

We have discovered distinct roles for the primary (A1) and secondary (A2) auditory cortices in the extraction of complex sound features: specifically, frequency modulation is extracted by A1, while A2 encodes the concurrent multifrequency spectrum.

In this perspective we discuss pre-clinical models of opioid use disorder and argue that we need to consider multiple models to fully understand the human condition.

In this paper we investigated sleep behavior, and patterns in mouse models of opioid use disorder. We investigated sleep behavior also following a sleep deprivation experiment in the same mice after a week of forced abstinence.

The effects of trauma (childhood sexual abuse) on rate of cognitive decline. The results indicate that epigenetic age acceleration has the potential to serve as a biomarker for cognitive decline in patients with a child maltreatment history or psychiatric disorders

Research from academic institutions is a significant driving force in developing new medical devices. In 2020, the Association of University Technology Managers (AUTM) reported 27,112 invention disclosures [1]. Despite these impressive efforts, disclosures do not translate into commercialized products due to numerous barriers, including weak support infrastructure and the lack...

Individuals with posttraumatic stress disorder (PTSD) are known to have signs of accelerated biological aging, but the meaning of this finding has been unclear. Using a gene signature of accelerated aging, this study for the first time showed that individuals with more advanced biological age at the time of trauma...

This study evaluated a novel psychosocial intervention that combined two evidence-based practices – motivational interviewing and cognitive-behavioral therapy (MI-CBT) – for the treatment of motivational negative symptoms. The results of the randomized-controlled trial showed that participants in the MI-CBT group showed significantly greater improvements in motivational negative symptoms over the...

Exposure to stressful life events proximal to the pubertal transition can expose directional effects of hormone change on affective symptoms. Specifically, greater affective symptoms were associated with increases in hormones in a high stress context and decreases in hormones in a low stress context. These findings provide support for a...

This study demonstrates that the success of psychotherapy aimed at reducing anhedonia is dependent on perceived stress and impacts perceived stress.