Category: Research Publications

Alcohol’s impairing effects on inhibitory control (a behavioral index of impulsivity) may partly account for heavy drinking and alcohol-related harms. This meta-analysis combined data from 69 human laboratory studies to establish the overall magnitude of alcohol’s effects on inhibitory control.

This study finds that lower levels of fatty acid amide hydrolase (FAAH) in the brain predict reduced sensitivity to negative effects of alcohol, greater urges to drink, and greater hazardous drinking in youth. These findings extend preclinical work by implicating the endocannabinoid system in relation to alcohol use disorder risk.

An invited review article on novel neurosteroids for the treatment of postpartum depression.

Task‐shifted, teacher‐led care may begin to bridge the child mental health care gap in low‐ and middle‐income countries by improving mental health literacy. We explore the perceived impact of RESEED (Responding to Students’ Emotions through Education) as a first step in programming for teachers to learn about mental health concepts...

Peripubertal female adolescents who are mood sensitive to changes in testosterone (i.e., experience increased mood symptoms with changes in testosterone) show disturbances in frontal brain activity important for cognitive control and blunted physiological responses to a psychosocial stress test.

People with schizophrenia and their high-risk, first-degree relatives report widespread episodic memory impairments that are purportedly due, at least in part, to failures of mnemonic discrimination. Here, we examined the status of mnemonic discrimination in 36 children and adolescents (aged 11-17 years) with and without familial risk for schizophrenia by...

Diagnosis and symptom severity in schizophrenia are associated with irregularities across neural oscillatory frequency bands, including theta, alpha, beta, and gamma. However, electroencephalographic signals consist of both periodic and aperiodic activity characterized by the (1/fX) shape in the power spectrum. In this paper, we investigated oscillatory and aperiodic activity differences...

In this study involving recent trauma-exposed civilians, researchers aimed to understand the complex relationship between substance use, posttraumatic stress disorder (PTSD), and depression. They utilized a large multisite dataset and tracked alcohol and cannabis use trajectories as well as PTSD and depression symptoms over a span of 3 months. The...

Evidence was insufficient to draw conclusions about the benefits or harms of anxiety screening programs. However, clear evidence exists that treatment for anxiety is beneficial, and more limited evidence indicates that some anxiety screening instruments have acceptable accuracy to detect generalized anxiety disorder.